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Effect of 2,3-Dimercaptopropanol (BAL) on Urinary Excretion and Brain Content of Mercury
  1. L. Magos
  1. Toxicology Research Unit, M.R.C. Laboratories, Carshalton, Surrey

    Abstract

    2,3-Dimercaptopropanol (BAL) given to rats in doses used for the treatment of acute mercury chloride poisoning in man increases the excretion of mercury. The mercury content of the brain was unaffected by 2,3-dimercaptopropanol unless it was given a short time after the mercuric chloride, when there was a 24% increase. The relevance of these findings to therapy with BAL is discussed.

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