The canonical role of messenger RNA (mRNA) is to deliver protein-coding information to
sites of protein synthesis. However, given that microRNAs bind to RNAs, we hypothesized …

Cancer susceptibility has been attributed to at least one heterozygous genetic alteration in a
tumor suppressor gene (TSG). It has been hypothesized that subtle variations in TSG …

Objectives: To assess the risks of reproductive disorders and birth defects in offspring of
male painters with exposure to organic solvents, and to determine the shape of the dose …

Despite important advances in critical care medicine during the last two decades, the
mortality rate of sepsis has remained high, probably because the pathogenesis of sepsis is …

Background Infected necrotising pancreatitis is a potentially lethal disease and an indication
for invasive intervention. The surgical step-up approach is the standard treatment. A …

Background Infected necrotizing pancreatitis is a potentially lethal disease that is treated
with the use of a step-up approach, with catheter drainage often delayed until the infected …

Importance For patients with painful chronic pancreatitis, surgical treatment is postponed
until medical and endoscopic treatment have failed. Observational studies have suggested …

Background Infected necrotising pancreatitis is a potentially lethal disease that nearly
always requires intervention. Traditionally, primary open necrosectomy has been the …

Background Transthoracic minimally invasive esophagectomy (MIE) is increasingly
performed as part of curative multimodality treatment. There appears to be no robust …

Short bowel syndrome (SBS) is a serious condition with considerable morbidity and
mortality. When treatment with parenteral nutrition fails and life-threatening complications …