Accuracy of FENO for diagnosing asthma: a systematic review

S Karrasch, K Linde, G Rücker, H Sommer… - Thorax, 2017 - thorax.bmj.com
Background Measurement of FENO might substitute bronchial provocation for diagnosing
asthma. We aimed to investigate the diagnostic accuracy of FENO measurement compared …

[HTML][HTML] Aging and induced senescence as factors in the pathogenesis of lung emphysema

S Karrasch, O Holz, RA Jörres - Respiratory medicine, 2008 - Elsevier
Classically, the development of emphysema in chronic obstructive pulmonary disease is
believed to involve inflammation induced by cigarette smoke and leukocyte activation …

Genome-wide association study identifies five loci associated with lung function

E Repapi, I Sayers, LV Wain, PR Burton, T Johnson… - Nature …, 2010 - nature.com
Pulmonary function measures are heritable traits that predict morbidity and mortality and
define chronic obstructive pulmonary disease (COPD). We tested genome-wide association …

[HTML][HTML] COVID-19 and heat waves: New challenges for healthcare systems

S Bose-O'Reilly, H Daanen, K Deering, N Gerrett… - Environmental …, 2021 - Elsevier
Heat waves and Covid-19 overlap, as this pandemic continues into summer 2021. Using a
narrative review, we identified overlapping risk groups and propose coping strategies. The …

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

N Shrine, AL Guyatt, AM Erzurumluoglu, VE Jackson… - Nature …, 2019 - nature.com
Reduced lung function predicts mortality and is key to the diagnosis of chronic obstructive
pulmonary disease (COPD). In a genome-wide association study in 400,102 individuals of …

Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology

MA Ferreira, JM Vonk, H Baurecht, I Marenholz… - Nature …, 2017 - nature.com
Asthma, hay fever (or allergic rhinitis) and eczema (or atopic dermatitis) often coexist in the
same individuals, partly because of a shared genetic origin,,. To identify shared risk variants …

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

MS Artigas, DW Loth, LV Wain, SA Gharib, M Obeidat… - Nature …, 2011 - nature.com
Pulmonary function measures reflect respiratory health and are used in the diagnosis of
chronic obstructive pulmonary disease. We tested genome-wide association with forced …

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

LV Wain, N Shrine, MS Artigas, AM Erzurumluoglu… - Nature …, 2017 - nature.com
Chronic obstructive pulmonary disease (COPD) is characterized by reduced lung function
and is the third leading cause of death globally. Through genome-wide association …

[HTML][HTML] Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary …

N Shrine, AG Izquierdo, J Chen, R Packer, RJ Hall… - Nature …, 2023 - nature.com
Lung-function impairment underlies chronic obstructive pulmonary disease (COPD) and
predicts mortality. In the largest multi-ancestry genome-wide association meta-analysis of …

Genome-wide association analysis identifies six new loci associated with forced vital capacity

DW Loth, MS Artigas, SA Gharib, LV Wain… - Nature …, 2014 - nature.com
Forced vital capacity (FVC), a spirometric measure of pulmonary function, reflects lung
volume and is used to diagnose and monitor lung diseases. We performed genome-wide …