[HTML][HTML] Epigenetic regulation of miRNA expression in malignant mesothelioma: miRNAs as biomarkers of early diagnosis and therapy

M Tomasetti, S Gaetani, F Monaco, J Neuzil… - Frontiers in …, 2019 - frontiersin.org
Asbestos exposure leads to epigenetic and epigenomic modifications that, in association
with ROS-induced DNA damage, contribute to cancer onset. Few miRNAs epigenetically …

[HTML][HTML] Exosomal miR-126 as a circulating biomarker in non-small-cell lung cancer regulating cancer progression

F Grimolizzi, F Monaco, F Leoni, M Bracci… - Scientific reports, 2017 - nature.com
Lung cancer is one of the leading causes of cancer-related deaths. It is diagnosed mostly at
the locally advanced or metastatic stage. Recently, micro RNAs (miRs) and their distribution …

[HTML][HTML] Peripheral skin temperature and circadian biological clock in shift nurses after a day off

M Bracci, V Ciarapica, A Copertaro… - International Journal of …, 2016 - mdpi.com
The circadian biological clock is essentially based on the light/dark cycle. Some people
working with shift schedules cannot adjust their sleep/wake cycle to the light/dark cycle, and …

Exosomal transfer of miR-126 promotes the anti-tumour response in malignant mesothelioma: Role of miR-126 in cancer-stroma communication

F Monaco, S Gaetani, F Alessandrini, A Tagliabracci… - Cancer letters, 2019 - Elsevier
MiR-126 has been shown to suppress malignant mesothelioma (MM) by targeting cancer-
related genes without inducing toxicity or histopathological changes. Exosomes provide the …

[HTML][HTML] MicroRNA-126 induces autophagy by altering cell metabolism in malignant mesothelioma

M Tomasetti, F Monaco, N Manzella, J Rohlena… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Autophagy favors both cell survival and cancer suppression, and increasing evidence
reveals that microRNAs (MIRs) regulate autophagy. Previously we reported that MIR126 is …

[HTML][HTML] Circulating inflamma-miRs as potential biomarkers of cognitive impairment in patients affected by Alzheimer's disease

A Giuliani, S Gaetani, G Sorgentoni… - Frontiers in aging …, 2021 - frontiersin.org
Alzheimer's disease (AD), the most prevalent neurodegenerative disease in the growing
population of elderly people, is still lacking minimally-invasive circulating biomarkers that …

Mechanism underlying the effect of long‐term exposure to low dose of pesticides on DNA integrity

R Alleva, N Manzella, S Gaetani… - Environmental …, 2018 - Wiley Online Library
Pesticides, including herbicides, insecticides and fungicides, are widely used in intensive
agriculture. Recently, the long‐term effects of pesticide exposure were found to be …

Four-miRNA signature to identify asbestos-related lung malignancies

L Santarelli, S Gaetani, F Monaco, M Bracci… - … Biomarkers & Prevention, 2019 - AACR
Background: Altered miRNA expression is an early event upon exposure to occupational/
environmental carcinogens; thus, identification of a novel asbestos-related profile of miRNAs …

DNA damage response in workers exposed to low-dose ionising radiation

S Gaetani, F Monaco, M Bracci, V Ciarapica… - Occupational and …, 2018 - oem.bmj.com
Objective Medical personnel using radiation for diagnosis and therapeutic purposes are
potentially at risk of cancer development. In this study, the effect of ionising radiation (IR) …

Organic honey supplementation reverses pesticide‐induced genotoxicity by modulating DNA damage response

R Alleva, N Manzella, S Gaetani… - Molecular nutrition & …, 2016 - Wiley Online Library
Scope Glyphosate (GLY) and organophosphorus insecticides such as chlorpyrifos (CPF)
may cause DNA damage and cancer in exposed individuals through mitochondrial …