Following a request from EFSA, the Panel on Plant Protection Products and their Residues
(PPR) developed an opinion on the state of the art of Toxicokinetic/Toxicodynamic (TKTD) …

New concerns about biodiversity, ecosystem services and human health triggered several
new regulations increasing the need for sound ecotoxicological risk assessment. The PEER …

Nonlinear regression models are applied in a broad variety of scientific fields. Various R
functions are already dedicated to fitting such models, among which the function nls () has a …

A review of in vitro genotoxicity studies on titanium dioxide nanoparticles (TiO2-NPs)
published between 2010 and 2016 was performed by France in the framework of the CLP …

The use of computers to deliver course-related materials is rapidly expanding in most
universities. Yet the effects of computer vs. printed delivery modes on students' performance …

Ubiquitous use of plasticizers has led to a widespread internal exposure of the European
population. Until today, metabolites are detected in almost every urine sample analysed …

In situ feeding assays implemented with transplanted crustacean gammarids have been
claimed as promising tools for the diagnostic assessment of water quality. Nevertheless the …

Abstract The General Unified Threshold model for Survival (GUTS) integrates previously
published toxicokinetic-toxicodynamic models and estimates survival with explicitly defined …

Bioassays can be used in aquatic toxicology to provide individual determinations, however
ecotoxicology is now attempting to assess the impact of pollution on populations. The main …

The acceptance and usefulness of simulation models are often limited by the efficiency,
transparency, reproducibility, and reliability of the modelling process. We address these …