The health effects of air pollution have been subject to intense study in recent years.
Exposure to pollutants such as airborne participate matter and ozone has been associated …

While asthma is considered an inflammatory disorder of the conducting airways, it is
becoming increasingly apparent that the disease is heterogeneous with respect to …

The recognition that asthma is primarily an inflammatory disorder of the airways associated
with T helper type 2 (TH2) cell-dependent promotion of IgE production and recruitment of …

Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal
Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve …

Objective: To study the association between upper and lower respiratory viral infections and
acute exacerbations of asthma in schoolchildren in the community. Design: Community …

Asthma is a common respiratory disorder characterized by recurrent episodes of coughing,
wheezing and breathlessness. Although environmental factors such as allergen exposure …

Summary Background Interleukin-5 (IL-5) is essential for the formation of eosinophils, which
are thought to have a major role in the pathogenesis of asthma and other allergic diseases …

Improving the reproducibility of biomedical research is a major challenge. Transparent and
accurate reporting is vital to this process; it allows readers to assess the reliability of the …

Abstract Background and Methods. Children with asthma commonly have positive skin tests
for inhaled allergens, and in the United Kingdom the majority of older children with asthma …

Rhinoviruses are the major cause of asthma exacerbations, and asthmatics have increased
susceptibility to rhinovirus and risk of invasive bacterial infections. Here we show deficient …