Technological and economic potential of poly (lactic acid) and lactic acid derivatives
R Datta, SP Tsai, P Bonsignore… - FEMS microbiology …, 1995 - academic.oup.com
Lactic acid has been an intermediate-volume specialty chemical (world production∼ 40,000
tons/yr) used in a wide range of food processing and industrial applications. Lactic acid has …
tons/yr) used in a wide range of food processing and industrial applications. Lactic acid has …
Minimum amount of physical activity for reduced mortality and extended life expectancy: a prospective cohort study
Background The health benefits of leisure-time physical activity are well known, but whether
less exercise than the recommended 150 min a week can have life expectancy benefits is …
less exercise than the recommended 150 min a week can have life expectancy benefits is …
Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index
JR Junutula, H Raab, S Clark, S Bhakta… - Nature …, 2008 - nature.com
Antibody-drug conjugates enhance the antitumor effects of antibodies and reduce adverse
systemic effects of potent cytotoxic drugs. However, conventional drug conjugation …
systemic effects of potent cytotoxic drugs. However, conventional drug conjugation …
All-cause mortality attributable to chronic kidney disease: a prospective cohort study based on 462 293 adults in Taiwan
Background Both end-stage renal disease and chronic kidney disease are increasing
worldwide; however, the full effect of chronic kidney disease is unknown because mortality …
worldwide; however, the full effect of chronic kidney disease is unknown because mortality …
Asbestos related diseases from environmental exposure to crocidolite in Da-yao, China. I. Review of exposure and epidemiological data
S Luo, X Liu, S Mu, SP Tsai, CP Wen - … and environmental medicine, 2003 - oem.bmj.com
Background: Scattered patches of crocidolite, one form of asbestos, were found in the
surface soil in the rural county of Da-yao in southwestern China. In 1983, researchers from …
surface soil in the rural county of Da-yao in southwestern China. In 1983, researchers from …
Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes
L Fu, LM John, SH Adams, XX Yu, E Tomlinson… - …, 2004 - academic.oup.com
Hormonal control of metabolic rate can be important in regulating the imbalance between
energy intake and expenditure that underlies the development of obesity. In mice fed a high …
energy intake and expenditure that underlies the development of obesity. In mice fed a high …
Are Asians at greater mortality risks for being overweight than Caucasians? Redefining obesity for Asians
ObjectivesTo assess whether overweight Asians, assessed on the basis of WHO criteria, are
at greater mortality risk than overweight Caucasians, and to determine whether alternative …
at greater mortality risk than overweight Caucasians, and to determine whether alternative …
Transgenic mice expressing human fibroblast growth factor-19 display increased metabolic rate and decreased adiposity
E Tomlinson, L Fu, L John, B Hultgren, X Huang… - …, 2002 - academic.oup.com
The fibroblast growth factors (FGFs), and the corresponding receptors, are implicated in
more than just the regulation of epithelial cell proliferation and differentiation. Specifically …
more than just the regulation of epithelial cell proliferation and differentiation. Specifically …
Anatomy of the healthy worker effect: a critical review
CP Wen, SP Tsai, RL Gibson - Journal of Occupational and …, 1983 - journals.lww.com
The healthy worker effect is the composite result from factors such as (1) selection of the
work force,(2) changes in lifestyle accompanying employment, and (3) methodological …
work force,(2) changes in lifestyle accompanying employment, and (3) methodological …
A mouse model of hepatocellular carcinoma: ectopic expression of fibroblast growth factor 19 in skeletal muscle of transgenic mice
K Nicholes, S Guillet, E Tomlinson, K Hillan… - The American journal of …, 2002 - Elsevier
Most mouse models of hepatocellular carcinoma have expressed growth factors and
oncogenes under the control of a liver-specific promoter. In contrast, we describe here the …
oncogenes under the control of a liver-specific promoter. In contrast, we describe here the …