The significance of white-coat hypertension in older persons with isolated systolic
hypertension remains poorly understood. We analyzed subjects from the population-based …

Background: Cardiovascular diseases (CVD) cause 1.8 million premature (< 75 years) death
annually in Europe. The majority of these deaths are preventable with the most efficient and …

Objectives The International Database on Ambulatory Blood Pressure Monitoring (1993–
1994) lacked a prospective dimension. We are constructing a new resource of longitudinal …

Objective To use the rs1229984 variant in the alcohol dehydrogenase 1B gene (ADH1B) as
an instrument to investigate the causal role of alcohol in cardiovascular disease. Design …

Background Statins increase the risk of new-onset type 2 diabetes mellitus. We aimed to
assess whether this increase in risk is a consequence of inhibition of 3-hydroxy-3 …

Context Extrapolations from observational studies and short-term intervention trials suggest
that population-wide moderation of salt intake might reduce cardiovascular events. Objective …

Although the number of insecure jobs has increased considerably over the recent decades,
relatively little is known about the health consequences of job insecurity, their international …

Background Statin treatment and variants in the gene encoding HMG-CoA reductase are
associated with reductions in both the concentration of LDL cholesterol and the risk of …

In previous studies, of which several were underpowered, the relation between
cardiovascular outcome and blood pressure (BP) variability was inconsistent. We followed …

Background We and other investigators previously reported that isolated nocturnal
hypertension on ambulatory measurement (INH) clustered with cardiovascular risk factors …