User profiles for "author:N C Chang"

Natasha C. Chang

McGill University
Verified email at mcgill.ca
Cited by 2557

Wnt signaling in myogenesis

J von Maltzahn, NC Chang, CF Bentzinger… - Trends in cell …, 2012 - cell.com
The formation of skeletal muscle is a tightly regulated process that is critically modulated by
Wnt signaling. Myogenesis is dependent on the precise and dynamic integration of multiple …

The endoplasmic reticulum in apoptosis and autophagy: role of the BCL-2 protein family

HM Heath-Engel, NC Chang, GC Shore - Oncogene, 2008 - nature.com
Apoptosis is essential for normal development and maintenance of homeostasis, and
disruption of apoptotic pathways is associated with multiple disease states, including cancer …

Host–transposon interactions: conflict, cooperation, and cooption

RL Cosby, NC Chang, C Feschotte - Genes & development, 2019 - genesdev.cshlp.org
Transposable elements (TEs) are mobile DNA sequences that colonize genomes and
threaten genome integrity. As a result, several mechanisms appear to have emerged during …

Inhibition of JAK-STAT signaling stimulates adult satellite cell function

FD Price, J Von Maltzahn, CF Bentzinger, NA Dumont… - Nature medicine, 2014 - nature.com
Diminished regenerative capacity of skeletal muscle occurs during adulthood. We identified
a reduction in the intrinsic capacity of mouse adult satellite cells to contribute to muscle …

The mechanism of recurrent laryngeal nerve injury during thyroid surgery—the application of intraoperative neuromonitoring

FY Chiang, IC Lu, WR Kuo, KW Lee, NC Chang… - Surgery, 2008 - Elsevier
BACKGROUND: Identification of recurrent laryngeal nerve (RLN) has decreased the rates of
permanent RLN palsy during thyroid operations; however, unexpected RLN palsy still …

Optical spectra, energy levels, and crystal‐field analysis of tripositive rare earth ions in Y2O3. I. Kramers ions in C2 sites

NC Chang, JB Gruber, RP Leavitt… - The Journal of Chemical …, 1982 - pubs.aip.org
Optical absorption and fluorescence spectra of the Kramers ions Ce3+, Sm3+, Dy3+, and
Yb3+ in the C, sites of Y, 03 are reported. A crystal-field analysis of these data and …

Antagonism of Beclin 1‐dependent autophagy by BCL‐2 at the endoplasmic reticulum requires NAF‐1

NC Chang, M Nguyen, M Germain, GC Shore - The EMBO journal, 2010 - embopress.org
In addition to mitochondria, BCL‐2 is located at the endoplasmic reticulum (ER) where it is a
constituent of several distinct complexes. Here, we identify the BCL‐2‐interacting protein at …

Dapagliflozin, a selective SGLT2 Inhibitor, attenuated cardiac fibrosis by regulating the macrophage polarization via STAT3 signaling in infarcted rat hearts

TM Lee, NC Chang, SZ Lin - Free Radical Biology and Medicine, 2017 - Elsevier
During myocardial infarction, infiltrated macrophages have pivotal roles in cardiac
remodeling and delayed M1 toward M2 macrophage phenotype transition is considered one …

[HTML][HTML] Orco mutagenesis causes loss of antennal lobe glomeruli and impaired social behavior in ants

W Trible, L Olivos-Cisneros, SK McKenzie, J Saragosti… - Cell, 2017 - cell.com
Life inside ant colonies is orchestrated with diverse pheromones, but it is not clear how ants
perceive these social signals. It has been proposed that pheromone perception in ants …

Role of interleukin-28B polymorphisms in the treatment of hepatitis C virus genotype 2 infection in Asian patients

ML Yu, CF Huang, JF Huang, NC Chang, JF Yang… - Hepatology, 2011 - journals.lww.com
Genome-wide association studies have linked single nucleotide polymorphisms (SNPs)
near the interleukin-28B gene to the hepatitis C virus genotype 1 (HCV-1) response to …