User profiles for "author:M Major"

Melanie Major

Resident in Plastic and Reconstructive Surgery, Johns Hopkins Hospital
Verified email at jhmi.edu
Cited by 1141

Racial differences in sarcoidosis incidence: a 5-year study in a health maintenance organization

BA Rybicki, M Major, J Popovich Jr… - American journal of …, 1997 - academic.oup.com
Reports of racial differences in the incidence of sarcoidosis, a granulomatous disorder of
unknown etiology, are pnmarily based on studies of military and veteran populations. To …

The molecular virology of hepatitis C

ME Major, SM Feinstone - Hepatology, 1997 - journals.lww.com
Hepatitis C virus (HCV), first identified in 1989, 1 is the structure. 10, 20 The proposed
secondary structure20, 21 is shown major causative agent of parenterally transmitted and …

Assessment of lateral cephalometric diagnosis of adenoid hypertrophy and posterior upper airway obstruction: a systematic review

MP Major, C Flores-Mir, PW Major - American journal of orthodontics and …, 2006 - Elsevier
Introduction: Our objective was to evaluate the capability of lateral cephalograms in
diagnosing hypertrophied adenoids and obstructed posterior nasopharyngeal airways …

Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase

IC Wang, YJ Chen, D Hughes, V Petrovic… - … and cellular biology, 2005 - Taylor & Francis
The Forkhead box m1 (Foxm1) gene is critical for G1/S transition and essential for mitotic
progression. However, the transcriptional mechanisms downstream of FoxM1 that control …

Neutralizing antibody response during acute and chronic hepatitis C virus infection

C Logvinoff, ME Major, D Oldach… - Proceedings of the …, 2004 - National Acad Sciences
Little is known about the role of Abs in determining the outcome of hepatitis C virus (HCV)
infection. By using infectious retroviral pseudotypes bearing HCV glycoproteins, we …

Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro

BD Lindenbach, P Meuleman, A Ploss… - Proceedings of the …, 2006 - National Acad Sciences
Hepatitis C virus (HCV) is a major cause of chronic liver disease, frequently progressing to
cirrhosis and increased risk of hepatocellular carcinoma. Current therapies are inadequate …

Distinct Wnt signaling pathways have opposing roles in appendage regeneration

CL Stoick-Cooper, G Weidinger, KJ Riehle, C Hubbert… - 2007 - journals.biologists.com
In contrast to mammals, lower vertebrates have a remarkable capacity to regenerate
complex structures damaged by injury or disease. This process, termed epimorphic …

Wilms tumor suppressor WTX negatively regulates WNT/ß-catenin signaling

MB Major, ND Camp, JD Berndt, XH Yi, SJ Goldenberg… - science, 2007 - science.org
Aberrant WNT signal transduction is involved in many diseases. In colorectal cancer and
melanoma, mutational disruption of proteins involved in the degradation of β-catenin, the …

Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor

VV Kalinichenko, ML Major, X Wang… - Genes & …, 2004 - genesdev.cshlp.org
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide.
Here, we provide evidence that the Forkhead Box (Fox) m1b (Foxm1b or Foxm1) …

Enhancement of mesenchymal stem cell angiogenic capacity and stemness by a biomimetic hydrogel scaffold

KC Rustad, VW Wong, M Sorkin, JP Glotzbach… - Biomaterials, 2012 - Elsevier
In this study, we examined the capacity of a biomimetic pullulan–collagen hydrogel to create
a functional biomaterial-based stem cell niche for the delivery of mesenchymal stem cells …