[HTML][HTML] Potential applications for sigma receptor ligands in cancer diagnosis and therapy
…, AA Rybczynska, NK Ramakrishnan, K Ishiwata… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Sigma receptors (sigma-1 and sigma-2) represent two independent classes of proteins.
Their endogenous ligands may include the hallucinogen N, N-dimethyltryptamine (DMT) …
Their endogenous ligands may include the hallucinogen N, N-dimethyltryptamine (DMT) …
PET tracers for imaging of the dopaminergic system
PH Elsinga, K Hatano, K Ishiwata - Current medicinal chemistry, 2006 - ingentaconnect.com
The dopaminergic system plays a major role in neurological and psychiatric disorders such
as Parkinson's disease, Huntington's disease, tardive dyskinea and schizophrenia …
as Parkinson's disease, Huntington's disease, tardive dyskinea and schizophrenia …
Sigma receptor ligands: possible application as therapeutic drugs and as radiopharmaceuticals
K Hashimoto, K Ishiwata - Current pharmaceutical design, 2006 - ingentaconnect.com
Sigma receptors are classified into sigma1 and sigma2 subtypes. These subtypes display a
different tissue distribution and a distinct physiological and pharmacological profile in the …
different tissue distribution and a distinct physiological and pharmacological profile in the …
[PDF][PDF] Intratumoral distribution of fluorine-18-fluorodeoxyglucose in vivo: high accumulation in macrophages and granulation tissues studied by microautoradiography
…, S Yamada, K Kubota, K Ishiwata… - Journal of Nuclear …, 1992 - Soc Nuclear Med
MBq) of [6-3Hjthymidine (3H-Thd, Amersham Japan Ltd., Ja pan) and killed 1 hr later. The
tumor was quickly dissected and prepared for frozen sectioning as reported previously (18) …
tumor was quickly dissected and prepared for frozen sectioning as reported previously (18) …
Basophils are essential initiators of a novel type of chronic allergic inflammation
…, K Mukai, Y Tsujimura, K Ishiwata… - Blood, The Journal …, 2007 - ashpublications.org
Basophils represent less than 1% of peripheral blood leukocytes and have often been
considered as minor and possibly redundant circulating mast cells. The recent finding that …
considered as minor and possibly redundant circulating mast cells. The recent finding that …
Selenosugars are key and urinary metabolites for selenium excretion within the required to low-toxic range
Y Kobayashi, Y Ogra, K Ishiwata… - Proceedings of the …, 2002 - National Acad Sciences
Essential micronutrient selenium is excreted into the urine and/or expired after being
transformed to methylated metabolites. Monomethylated selenium is excreted into the urine …
transformed to methylated metabolites. Monomethylated selenium is excreted into the urine …
[HTML][HTML] Selective ablation of basophils in mice reveals their nonredundant role in acquired immunity against ticks
T Wada, K Ishiwata, H Koseki, T Ishikura… - The Journal of …, 2010 - Am Soc Clin Investig
Ticks are ectoparasitic arthropods that can transmit a variety of microorganisms to humans
and animals during blood feeding, causing serious infectious disorders, including Lyme …
and animals during blood feeding, causing serious infectious disorders, including Lyme …
Aortic wall inflammation due to Takayasu arteritis imaged with 18F-FDG PET coregistered with enhanced CT
…, K Oda, T Nariai, Y Tanaka, K Ishiwata… - Journal of Nuclear …, 2005 - Soc Nuclear Med
The purpose of this study was to evaluate the ability of 18F-FDG PET to identify aortitis and
to localize and follow disease activity in patients with Takayasu arteritis. The value of using …
to localize and follow disease activity in patients with Takayasu arteritis. The value of using …
[PDF][PDF] Differential diagnosis of lung tumor with positron emission tomography: a prospective study
…, T Fujiwara, M Ito, J Hatazawa, K Ishiwata… - Journal of Nuclear …, 1990 - Soc Nuclear Med
Ff93 1/04 (CTI, Knoxville, TN) was used for 30 of the 46 patients. When it was out of service
or was occupied by other patients, ECAT II (EG & 0, Ortec, Oak Ridge, TN) was used for …
or was occupied by other patients, ECAT II (EG & 0, Ortec, Oak Ridge, TN) was used for …
[HTML][HTML] Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway
T Yamamoto, N Takano, K Ishiwata, M Ohmura… - Nature …, 2014 - nature.com
Abstract Haem oxygenase (HO)-1/carbon monoxide (CO) protects cancer cells from
oxidative stress, but the gas-responsive signalling mechanisms remain unknown. Here we …
oxidative stress, but the gas-responsive signalling mechanisms remain unknown. Here we …