Background Use of self-expanding metallic stents (SEMS) as a bridge to surgery has been
suggested as an alternative management for acute malignant left-sided colonic obstruction …

The profession of genetic counseling (also called genetic counselling in many countries)
began nearly 50 years ago in the United States, and has grown internationally in the past 30 …

Background Ulcerative Colitis (UC) is an inflammatory condition affecting the colon with an
incidence of approximately 10‐20 per 100,000 per year. No existing intervention is effective …

Chromosome 21 is the smallest human autosome. An extra copy of chromosome 21 causes
Down syndrome, the most frequent genetic cause of significant mental retardation, which …

The RNA moieties of ribonuclease P purified from both E. coli (Ml RNA) and B. subtilis (P-
RNA) can cleave tRNA precursor molecules in buffers containing either 60 mM Mg*+ or 10 …

Familial platelet disorder with predisposition to acute myelogenous leukaemia (FPD/AML,
MIM 601399) is an autosomal dominant disorder characterized by qualitative and …

Abstract In the United States, estimates indicate there are between 250,000 and 400,000
individuals with Down syndrome (DS), and nearly all will develop Alzheimer's disease (AD) …

The cellular receptor for the alpha/beta interferons contains at least two components that
interact with interferon. The ifnar1 component is well characterized and a putative ifnar2 …

Quantitative and qualitative disturbances in faecal flora suggest a role for enteric bacteria
and their products in the pathogenesis of inflammatory bowel disease (IBD). This study …

Symptom intensity in cancer and palliative care patients is frequently assessed using a 0–10
ranking score. Results are then often grouped into verbal categories (mild, moderate, or …