HIV infection and tuberculosis in South Africa: an urgent need to escalate the public health response
One of the greatest challenges facing post-apartheid South Africa is the control of the
concomitant HIV and tuberculosis epidemics. HIV continues to spread relentlessly, and …
concomitant HIV and tuberculosis epidemics. HIV continues to spread relentlessly, and …
The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis
Global tuberculosis incidence has declined marginally over the past decade, and
tuberculosis remains out of control in several parts of the world including Africa and Asia …
tuberculosis remains out of control in several parts of the world including Africa and Asia …
Tuberculosis in sub-Saharan Africa: opportunities, challenges, and change in the era of antiretroviral treatment
EL Corbett, B Marston, GJ Churchyard, KM De Cock - The Lancet, 2006 - thelancet.com
Rapid scale-up of antiretroviral treatment programmes is happening in Africa, driven by
international advocacy and policy directives and supported by unprecedented donor funding …
international advocacy and policy directives and supported by unprecedented donor funding …
[HTML][HTML] The diarylquinoline TMC207 for multidrug-resistant tuberculosis
Background The diarylquinoline TMC207 offers a new mechanism of antituberculosis action
by inhibiting mycobacterial ATP synthase. TMC207 potently inhibits drug-sensitive and drug …
by inhibiting mycobacterial ATP synthase. TMC207 potently inhibits drug-sensitive and drug …
The geographic diversity of nontuberculous mycobacteria isolated from pulmonary samples: an NTM-NET collaborative study
W Hoefsloot, J Van Ingen, C Andrejak… - European …, 2013 - Eur Respiratory Soc
A significant knowledge gap exists concerning the geographical distribution of
nontuberculous mycobacteria (NTM) isolation worldwide. To provide a snapshot of NTM …
nontuberculous mycobacteria (NTM) isolation worldwide. To provide a snapshot of NTM …
[HTML][HTML] Development of a standardized screening rule for tuberculosis in people living with HIV in resource-constrained settings: individual participant data meta …
H Getahun, W Kittikraisak, CM Heilig, EL Corbett… - PLoS …, 2011 - journals.plos.org
Background The World Health Organization recommends the screening of all people living
with HIV for tuberculosis (TB) disease, followed by TB treatment, or isoniazid preventive …
with HIV for tuberculosis (TB) disease, followed by TB treatment, or isoniazid preventive …
[HTML][HTML] High-dose rifapentine with moxifloxacin for pulmonary tuberculosis
A Jindani, TS Harrison, AJ Nunn… - … England Journal of …, 2014 - Mass Medical Soc
Background Tuberculosis regimens that are shorter and simpler than the current 6-month
daily regimen are needed. Methods We randomly assigned patients with newly diagnosed …
daily regimen are needed. Methods We randomly assigned patients with newly diagnosed …
[HTML][HTML] A trial of mass isoniazid preventive therapy for tuberculosis control
GJ Churchyard, KL Fielding, JJ Lewis… - … England Journal of …, 2014 - Mass Medical Soc
Background Tuberculosis is epidemic among workers in South African gold mines. We
evaluated an intervention to interrupt tuberculosis transmission by means of mass screening …
evaluated an intervention to interrupt tuberculosis transmission by means of mass screening …
Achieving the health Millennium Development Goals for South Africa: challenges and priorities
Summary 15 years after liberation from apartheid, South Africans are facing new challenges
for which the highest calibre of leadership, vision, and commitment is needed. The effect of …
for which the highest calibre of leadership, vision, and commitment is needed. The effect of …
Safety and efficacy of the HVTN 503/Phambili study of a clade-B-based HIV-1 vaccine in South Africa: a double-blind, randomised, placebo-controlled test-of-concept …
GE Gray, M Allen, Z Moodie, G Churchyard… - The Lancet infectious …, 2011 - thelancet.com
Summary Background The MRKAd5 HIV-1 gag/pol/nef subtype B vaccine was designed to
elicit T-cell-mediated immune responses capable of providing complete or partial protection …
elicit T-cell-mediated immune responses capable of providing complete or partial protection …