Clinical studies with oral lipid based formulations of poorly soluble compounds

DG Fatouros, DM Karpf, FS Nielsen… - … and clinical risk …, 2007 - Taylor & Francis
This work is an attempt to give an overview of the clinical data available on lipid based
formulations. Lipid and surfactant based formulations are recognized as a feasible approach …

Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists

T Honore, SN Davies, J Drejer, EJ Fletcher… - Science, 1988 - science.org
The N-methyl-D-aspartate (NMDA)-subtype of glutamate receptors has been well described
as a result of the early appearance of NMDA antagonists, but no potent antagonist for the" …

Plasma malondialdehyde as biomarker for oxidative stress: reference interval and effects of life-style factors

F Nielsen, BB Mikkelsen, JB Nielsen… - Clinical …, 1997 - academic.oup.com
Malondialdehyde (MDA) is one of the most frequently used indicators of lipid peroxidation.
To generate reliable reference intervals for plasma malondialdehyde (P-MDA), a reference …

Discovery of the once-weekly glucagon-like peptide-1 (GLP-1) analogue semaglutide

J Lau, P Bloch, L Schäffer, I Pettersson… - Journal of medicinal …, 2015 - ACS Publications
Liraglutide is an acylated glucagon-like peptide-1 (GLP-1) analogue that binds to serum
albumin in vivo and is approved for once-daily treatment of diabetes as well as obesity. The …

Serum vaccine antibody concentrations in children exposed to perfluorinated compounds

P Grandjean, EW Andersen, E Budtz-Jørgensen… - Jama, 2012 - jamanetwork.com
Context Perfluorinated compounds (PFCs) have emerged as important food contaminants.
They cause immune suppression in a rodent model at serum concentrations similar to those …

Paramagnetic lanthanide (III) complexes as pH‐sensitive chemical exchange saturation transfer (CEST) contrast agents for MRI applications

S Aime, A Barge, D Delli Castelli… - … in Medicine: An …, 2002 - Wiley Online Library
The recently introduced new class of contrast agents (CAs) based on chemical exchange
saturation transfer (CEST) may have a huge potential for the development of novel …

Albuminuria and poor glycemic control predict mortality in NIDDM

MA Gall, K Borch-Johnsen, P Hougaard, FS Nielsen… - Diabetes, 1995 - Am Diabetes Assoc
The impact of microalbuminuria and macroalbuminuria on mortality was evaluated
prospectively in 328 Caucasian patients with non-insulin-dependent diabetes mellitus …

[HTML][HTML] Biomonitoring of Danish school children and mothers including biomarkers of PBDE and glyphosate

LE Knudsen, PW Hansen, S Mizrak… - Reviews on …, 2017 - degruyter.com
Background: The Danish part of the large European Human biomonitoring pilot project
Demonstration of a study to Coordinate and Perform Human biomonitoring on a European …

Antioxidative enzyme activities in human erythrocytes

HR Andersen, JB Nielsen, F Nielsen… - Clinical …, 1997 - academic.oup.com
Reliable and standardized methods are necessary to determine the expression of
antioxidative enzymes and their role in maintaining health. In addition, the variability of the …

Partition of environmental chemicals between maternal and fetal blood and tissues

LL Needham, P Grandjean, B Heinzow… - … science & technology, 2011 - ACS Publications
Passage of environmental chemicals across the placenta has important toxicological
consequences, as well as for choosing samples for analysis and for interpreting the results …