In humans, cancer may be caused by genetics and environmental exposures; however, in
the majority of instances the identification of the critical time window of exposure is …

Roman E & Smith AG (2011) Histopathology 58, 4–14 Epidemiology of lymphomas
Epidemiological reports on lymphomas often begin, and sometimes end, by stating that little …

Haematological malignancies are complex diseases, affecting the entire age spectrum, and
having marked differences in presentation, treatment, progression and outcome. Patients …

Purpose Rearrangement of MYC occurs in a proportion of diffuse large B-cell lymphomas
(DLBCL), where they may be associated with an adverse clinical outcome. The aim of this …

Reduction of 5, 10-methylenetetrahydrofolate (methyleneTHF), a donor for methylating
dUMP to dTMP in DNA synthesis, to 5-methyltetrahydrofolate (methylTHF), the primary …

To identify risk variants for childhood acute lymphoblastic leukemia (ALL), we conducted a
genome-wide association study of two case-control series, analyzing the genotypes with …

Background Common genetic variants in immune and inflammatory response genes can
affect the risk of developing non-Hodgkin lymphoma. We aimed to test this hypothesis using …

Based on the profile of genetic alterations occurring in tumor samples from selected diffuse
large B-cell lymphoma (DLBCL) patients, 2 recent whole-exome sequencing studies …

Abstract Background Non-Hodgkin lymphoma (NHL) comprises biologically and clinically
heterogeneous subtypes. Previously, study size has limited the ability to compare and …

Glutathione S-transferases (GSTs) detoxify potentially mutagenic and toxic DNA-reactive
electrophiles, including metabolites of several chemotherapeutic agents, some of which are …