[PDF][PDF] Oncology meets immunology: the cancer-immunity cycle
The genetic and cellular alterations that define cancer provide the immune system with the
means to generate T cell responses that recognize and eradicate cancer cells. However …
means to generate T cell responses that recognize and eradicate cancer cells. However …
Elements of cancer immunity and the cancer–immune set point
Immunotherapy is proving to be an effective therapeutic approach in a variety of cancers. But
despite the clinical success of antibodies against the immune regulators CTLA4 and PD …
despite the clinical success of antibodies against the immune regulators CTLA4 and PD …
Bone morphogenetic proteins
DI Chen, M Zhao, GR Mundy - Growth factors, 2004 - Taylor & Francis
Bone morphogenetic proteins (BMPs) are multi-functional growth factors that belong to the
transforming growth factor β (TGFβ) superfamily. The roles of BMPs in embryonic …
transforming growth factor β (TGFβ) superfamily. The roles of BMPs in embryonic …
Beyond the imitation game: Quantifying and extrapolating the capabilities of language models
…, D Perszyk, D Hernandez, D Chen… - arXiv preprint arXiv …, 2022 - arxiv.org
Language models demonstrate both quantitative improvement and new qualitative
capabilities with increasing scale. Despite their potentially transformative impact, these new …
capabilities with increasing scale. Despite their potentially transformative impact, these new …
Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
The development of human cancer is a multistep process characterized by the accumulation
of genetic and epigenetic alterations that drive or reflect tumour progression. These changes …
of genetic and epigenetic alterations that drive or reflect tumour progression. These changes …
[HTML][HTML] Compassionate use of remdesivir for patients with severe Covid-19
…, S Ahmed, J Bernett, D Chelliah, D Chen… - … England Journal of …, 2020 - Mass Medical Soc
Background Remdesivir, a nucleotide analogue prodrug that inhibits viral RNA
polymerases, has shown in vitro activity against SARS-CoV-2. Methods We provided …
polymerases, has shown in vitro activity against SARS-CoV-2. Methods We provided …
Atezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK): a phase 3, open-label, multicentre randomised controlled trial
A Rittmeyer, F Barlesi, D Waterkamp, K Park… - The Lancet, 2017 - thelancet.com
Background Atezolizumab is a humanised antiprogrammed death-ligand 1 (PD-L1)
monoclonal antibody that inhibits PD-L1 and programmed death-1 (PD-1) and PD-L1 and …
monoclonal antibody that inhibits PD-L1 and programmed death-1 (PD-1) and PD-L1 and …
Lamda: Language models for dialog applications
We present LaMDA: Language Models for Dialog Applications. LaMDA is a family of
Transformer-based neural language models specialized for dialog, which have up to 137B …
Transformer-based neural language models specialized for dialog, which have up to 137B …
Asian emissions in 2006 for the NASA INTEX-B mission
…, IS Park, S Reddy, JS Fu, D Chen… - Atmospheric …, 2009 - acp.copernicus.org
A new inventory of air pollutant emissions in Asia in the year 2006 is developed to support
the Intercontinental Chemical Transport Experiment-Phase B (INTEX-B) funded by the …
the Intercontinental Chemical Transport Experiment-Phase B (INTEX-B) funded by the …
Neuronal ensemble control of prosthetic devices by a human with tetraplegia
…, JA Mukand, M Saleh, AH Caplan, A Branner, D Chen… - Nature, 2006 - nature.com
Neuromotor prostheses (NMPs) aim to replace or restore lost motor functions in paralysed
humans by routeing movement-related signals from the brain, around damaged parts of the …
humans by routeing movement-related signals from the brain, around damaged parts of the …