[PDF][PDF] Front-line transplantation program with lenalidomide, bortezomib, and dexamethasone combination as induction and consolidation followed by lenalidomide …
…, D Caillot, C Fruchart, AM Stoppa, C Gentil… - J Clin …, 2014 - researchgate.net
Purpose The three-drug combination of lenalidomide, bortezomib, and dexamethasone
(RVD) has shown significant efficacy in multiple myeloma (MM). The Intergroupe …
(RVD) has shown significant efficacy in multiple myeloma (MM). The Intergroupe …
Post–COVID-19 conditions among children 90 days after SARS-CoV-2 infection
AL Funk, N Kuppermann, TA Florin… - JAMA Network …, 2022 - jamanetwork.com
Importance Little is known about the risk factors for, and the risk of, developing post–COVID-
19 conditions (PCCs) among children. Objectives To estimate the proportion of SARS-CoV-2 …
19 conditions (PCCs) among children. Objectives To estimate the proportion of SARS-CoV-2 …
Chronic effects of shift work on cognition: findings from the VISAT longitudinal study
Objectives Shift work, like chronic jet lag, is known to disrupt workers' normal circadian
rhythms and social life, and to be associated with increased health problems (eg, ulcers …
rhythms and social life, and to be associated with increased health problems (eg, ulcers …
DNA polymerase θ up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability
…, MJ Pillaire, A Bieth, C Gentil… - Proceedings of the …, 2010 - National Acad Sciences
“Replicative stress” is one of the main factors underlying neoplasia from its early stages.
Genes involved in DNA synthesis may therefore represent an underexplored source of …
Genes involved in DNA synthesis may therefore represent an underexplored source of …
[HTML][HTML] Quantitative single-cell proteomics as a tool to characterize cellular hierarchies
…, N Üresin, N Rapin, S Savickas, C Gentil… - Nature …, 2021 - nature.com
Large-scale single-cell analyses are of fundamental importance in order to capture
biological heterogeneity within complex cell systems, but have largely been limited to RNA …
biological heterogeneity within complex cell systems, but have largely been limited to RNA …
[PDF][PDF] Identification of a nuclear exosome decay pathway for processed transcripts
…, M Domanski, E Karadoulama, Y Chen, C Gentil… - Molecular cell, 2016 - cell.com
The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate
targeting is facilitated by its co-factor Mtr4p/hMTR4, which links to RNA-binding protein …
targeting is facilitated by its co-factor Mtr4p/hMTR4, which links to RNA-binding protein …
[HTML][HTML] Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in …
…, C Touriol, Y Nicaise, C Gentil… - Acta neuropathologica …, 2014 - Springer
Background The accumulation of beta amyloid (Aβ) peptides, a hallmark of Alzheimer's
disease (AD) is related to mechanisms leading to neurodegeneration. Among its pleiotropic …
disease (AD) is related to mechanisms leading to neurodegeneration. Among its pleiotropic …
A 'DNA replication'signature of progression and negative outcome in colorectal cancer
MJ Pillaire, J Selves, K Gordien, PA Gouraud, C Gentil… - Oncogene, 2010 - nature.com
Colorectal cancer is one of the most frequent cancers worldwide. As the tumor-node-
metastasis (TNM) staging classification does not allow to predict the survival of patients in …
metastasis (TNM) staging classification does not allow to predict the survival of patients in …
Higher mental stimulation at work is associated with improved cognitive functioning in both young and older workers
…, LR Duarte, P Bessières, C Dalm, C Gentil… - Ergonomics, 2010 - Taylor & Francis
The study examined whether mental stimulation received in the workplace positively affects
cognitive functioning and rate of cognitive change. Data taken from the VISAT (ageing …
cognitive functioning and rate of cognitive change. Data taken from the VISAT (ageing …
Deletion of the 1p32 region is a major independent prognostic factor in young patients with myeloma: the IFM experience on 1195 patients
…, D Caillot, G Marit, L Karlin, C Hulin, C Gentil… - Leukemia, 2014 - nature.com
Deletions of the 1p region appear as a pejorative prognostic factor in multiple myeloma
patients (especially 1p22 and 1p32 deletions) but there is a lack of data on the real impact of …
patients (especially 1p22 and 1p32 deletions) but there is a lack of data on the real impact of …