Abstract
Experimental animal studies have shown N-nitroso compounds (NOC) to be potent carcinogens. Epidemiologic evidence of the carcinogenic potential of dietary NOC and precursor nitrates and nitrites in humans remains inconclusive with regard to the risk of stomach, brain, esophageal, and nasopharyngeal cancers. Inadequate available data could obscure a small to moderate effect of NOC.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Carcinogens / administration & dosage
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Carcinogens / adverse effects*
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Case-Control Studies
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Diet / adverse effects*
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Food Contamination
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Humans
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Neoplasms / chemically induced*
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Neoplasms / epidemiology
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Nitrates / administration & dosage
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Nitrates / adverse effects*
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Nitrites / administration & dosage
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Nitrites / adverse effects*
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Nitroso Compounds / administration & dosage
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Nitroso Compounds / adverse effects*
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Risk Factors
Substances
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Carcinogens
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Nitrates
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Nitrites
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Nitroso Compounds