Lead in finger-bone analysed in vivo in active and retired lead workers

Am J Ind Med. 1984;6(6):447-57. doi: 10.1002/ajim.4700060608.

Abstract

In 75 active lead workers the median lead level in finger-bone (bone-Pb), as determined in vivo by an X-ray fluorescence method, was 43 micrograms/g (range less than 20-122). In 32 retired workers the median level was even higher, 59 micrograms/g (range less than 20-135), which indicates a slow turnover rate of lead in finger-bone. This was confirmed in 18 of the "active" workers, in whom bone-Pb was studied in connection with an exposure-free period. In spite of a significant decrease in blood-lead levels (B-Pb), no systematic change of bone-Pb occurred. There was an increase of bone-Pb with time of employment, but with a large interindividual variation. No association was found between bone-Pb and present B-Pb in the active lead workers. However, in the retired ones, B-Pb rose with increasing bone-Pb. The bone-lead pool thus causes an "internal" lead exposure.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Bone and Bones / analysis*
  • Environmental Exposure
  • Fingers
  • Humans
  • Lead / analysis*
  • Lead / metabolism
  • Male
  • Middle Aged
  • Occupations
  • Regression Analysis
  • Retirement
  • Time Factors

Substances

  • Lead