Abstract
We report on a patient with asthma induced by occupational exposure to alpha-amylase derived from Aspergillus oryzae, which is a component of bread additives. A type I hypersensitivity to this enzyme was demonstrated by means of skin test, immunoassay for specific IgE, and immediate bronchial provocation test response to an alpha-amylase extract.
MeSH terms
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Adult
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Aspergillus oryzae
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Asthma / etiology*
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Asthma / immunology
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Bread*
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Bronchial Provocation Tests
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Humans
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Hypersensitivity, Immediate / etiology
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Hypersensitivity, Immediate / immunology
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Immunoglobulin E / analysis
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Male
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Occupational Diseases / etiology*
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Occupational Diseases / immunology
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Skin Tests
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Spain
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alpha-Amylases / adverse effects*
Substances
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Immunoglobulin E
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alpha-Amylases