The aim of this study was to assess the prevalence, management and impact on quality of life of chronic musculoskeletal pain in Ireland by comparing the attitudes and perceptions of sufferers to those of general practice doctors (GPs). A telephone survey was conducted with 498 people with chronic musculoskeletal pain (screened from a total of 3323) and 150 GPs selected randomly from the medical register. The survey was based on a structured questionnaire that asked about the impact of CMP, usual management and perceived benefits and risks of treatment. Chronic musculoskeletal pain, including arthritis, affected one in six of the people screened for the survey. 25% of those surveyed have never consulted a doctor about their condition and many others will have waited up to two years before seeking help. 67% of respondents reported that pain caused significant reduction in their quality of life (measured using the SF-12 scale). The survey also indicated that people with chronic musculoskeletal pain have misconceptions about their condition, treatment options and side effects and patients rarely receive written information from their GP on these subjects. Chronic musculoskeletal pain, including arthritis is common and significantly reduces quality of life in Ireland. People delay seeking medical help, despite being in constant/daily pain. Written information is sparse and misperceptions relating to treatment are common. Improved awareness and valid information may lead to better care for people suffering from CMP in Ireland.