Neuropathy following acute intoxication with Mecarbam (OP ester)

E Stamboulis; A Psimaras; D Vassilopoulos; P Davaki; P Manta; E Kapaki

doi:10.1111/j.1600-0404.1991.tb04677.x

Neuropathy following acute intoxication with Mecarbam (OP ester)

Acta Neurol Scand. 1991 Mar;83(3):198-200. doi: 10.1111/j.1600-0404.1991.tb04677.x.

Authors

E Stamboulis¹, A Psimaras, D Vassilopoulos, P Davaki, P Manta, E Kapaki

Affiliation

¹ Department of Neurology, University of Athens, Greece.

PMID: 1851595
DOI: 10.1111/j.1600-0404.1991.tb04677.x

Abstract

Only a small number of organophosphorous compounds, of the many thousands circulating on the market, has been reported as causing neuropathy with delayed onset. A case is presented of a young male who in an attempt to commit suicide by taking a massive dose of Mecarbam, developed polyneuropathy accompanied by a mild involvement of the CNS. Mecarbam is herewith reported for the first time as an agent which can affect the peripheral nervous system.

Publication types

Case Reports

MeSH terms

Adult
Dose-Response Relationship, Drug
Electromyography / drug effects
Follow-Up Studies
Humans
Insecticides*
Male
Motor Neurons / drug effects
Neurologic Examination
Neuromuscular Diseases / chemically induced*
Neuromuscular Diseases / diagnosis
Organophosphate Poisoning*
Organothiophosphates
Reaction Time / drug effects
Suicide, Attempted*
Synaptic Transmission / drug effects

Substances

Insecticides
Organothiophosphates
mecarbam