Abstract
Objective:
The objective of this study was to determine if there is an additional risk of developing Hodgkin lymphoma, multiple myeloma, or soft tissue sarcoma as a consequence of exposure to a combination of phenoxyherbicides, rubber gloves, DEET (N, N-diethyl-m-toluamide), and sunlight compared with each of the individual chemicals.
Methods:
This was a population-based study of men with specific cancers and age, province-matched control subjects.
Results:
No additional risk from these combinations of exposures of developing these three types of tumor was found in contrast to non-Hodgkin lymphoma.
Conclusions:
The mechanisms by which phenoxyherbicides contribute to the risk of multiple myeloma and non-Hodgkin lymphoma may be different.
Publication types
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Multicenter Study
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Research Support, Non-U.S. Gov't
MeSH terms
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2,4-Dichlorophenoxyacetic Acid / adverse effects
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2-Methyl-4-chlorophenoxyacetic Acid / adverse effects
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2-Methyl-4-chlorophenoxyacetic Acid / analogs & derivatives
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Adult
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Agricultural Workers' Diseases / chemically induced*
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Agricultural Workers' Diseases / epidemiology
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Canada / epidemiology
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Case-Control Studies
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DEET / adverse effects*
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Dicamba / adverse effects
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Gloves, Protective / adverse effects
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Herbicides / adverse effects*
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Hodgkin Disease / chemically induced*
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Hodgkin Disease / epidemiology
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Humans
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Insect Repellents / adverse effects*
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Male
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Masks / adverse effects
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Multiple Myeloma / chemically induced*
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Multiple Myeloma / epidemiology
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Occupational Exposure / adverse effects*
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Occupational Exposure / statistics & numerical data
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Protective Clothing
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Risk Factors
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Rubber / adverse effects
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Sarcoma / chemically induced*
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Sarcoma / epidemiology
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Sunlight / adverse effects
Substances
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Herbicides
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Insect Repellents
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DEET
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2,4-Dichlorophenoxyacetic Acid
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mecoprop
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Rubber
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2-Methyl-4-chlorophenoxyacetic Acid
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Dicamba