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Blood borne viral infections among Danish Health Care Workers – frequent blood exposure but low prevalence of infection

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Abstract

Denmark is a country with low prevalence and incidence of blood borne viral infections. Among health care workers (HCWs) vaccination for hepatitis B is only offered to high-risk groups. The aims of this cross sectional survey were to determine the prevalence of hepatitis B, -C, and human immunodeficiency virus (HIV) among the staff at a Danish University hospital and to correlate this with risk factors for transmission. Additionally, we wanted to examine the current frequency of blood exposure, reporting habits and hepatitis B vaccination status in the staff. Of 1439 eligible hospital staffs included, 960 (67%) were HCWs. The overall human immunodeficiency virus (HIV)-, hepatitis C Virus (HCV)- and hepatitis B Virus (HBV)-prevalence was 0% (0/1439), 0.14% (2/1439) and 1.6% (23/1439), respectively. Twenty-three percent of HCWs were vaccinated against HBV. Age, blood transfusion and stay in endemic areas were associated independently to HBV infection as opposed to job-category, duration of employment, HBV vaccination status and blood exposure. Based on a 4-week recall period, the incidence of percutaneous blood exposure was 1.5/person-year. In conclusion the HIV and hepatitis prevalence was low despite frequent blood exposure and the principal risk factors were unrelated to work. Danish HCWs do not seem to be at increased risk of hepatitis B even though universal HBV vaccination has not been implemented.

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References

  1. Gerberding JL. Management of occupational exposures to blood-borne viruses. N Engl J Med 1995; 332: 444-451.

    Google Scholar 

  2. Beltrami EM, Williams IT, Shapiro CN, Chamberland ME. Risk and management of blood-borne infections in health care workers. Clin Microbiol Rev 2000; 13: 385-407.

    Google Scholar 

  3. Centers for Disease Control and Prevention. Updated US Public Health Service guidelines for the management of occupational exposures to HBV, HCV, and HIV and recommendations for postexposure prophylaxis. MMWR Morb Mortal Wkly Rep 2001; 50(RR-11): 1-52.

    Google Scholar 

  4. Christensen PB, Titlestad IL, Homburg KM, Georgsen J, Kristensen T. Hepatitis B core antibodies in Danish blood donors: A surrogate marker of risk behaviour. Vox Sanguinis 2001; 81: 222-227.

    Google Scholar 

  5. Iwarson S. Report from Working Group 3 (the Czech Republic, Denmark, Finland, Norway, The Netherlands, Slovakia, Sweden and the UK). Vaccine 1998; 16 (Suppl 1): S63-S64.

    Google Scholar 

  6. Nelsing S, Wantzin P, Skot J, et al. The seroprevalence of hepatitis B and C in hospitalized Danish patients. Scand J Infect Dis 1995; 27: 445-448.

    Google Scholar 

  7. Christensen PB. Epidemiology of hepatitis C. Ugeskr Laeger 1998; 160: 3529-3532.

    Google Scholar 

  8. SundhedsStyrelsen. Hepatitisvejledning. 31-1-1996.

  9. Krarup HB, Drewes AM, Madsen PH. A quantitative HCV-PCR test for routine diagnostics. Scand J Clin Lab Invest 1998; 58: 415-422.

    Google Scholar 

  10. Christenson B, Bottiger M, Grillner L. The prevalence of hepatitis B in Sweden; a statistical serosurvey of 3381 Swedish inhabitants. Epidemiol Infect 1997; 119: 221-225.

    Google Scholar 

  11. Jefferson T, Demicheli V, Deeks J, MacMillan A, Sassi F, Pratt M. Vaccines for preventing hepatitis B in health-care workers (Cochrane Review). The Cochrane Library, Issue 4, 2001. Oxford: Update Software, 1997.

    Google Scholar 

  12. Christenson B. Acute infections with hepatitis B virus in medical personnel during a 15-year follow-up. Am J Epidemiol 1985; 122: 411-417.

    Google Scholar 

  13. Mahoney FJ, Stewart K, Hu H, Coleman P, Alter MJ. Progress toward the elimination of hepatitis B virus transmission among health care workers in the United States. Arch Intern Med 1997; 157: 2601-2605.

    Google Scholar 

  14. Beekmann SE, Vlahov D, Koziol DE, McShalley ED, Schmitt JM, Henderson DK. Temporal association between implementation of universal precautions and a sustained, progressive decrease in percutaneous exposures to blood. Clin Infect Dis 1994; 18: 562-569.

    Google Scholar 

  15. Kristensen MS, Wernberg NM, Anker-Moller E. Healthcare workers' risk of contact with body fluids in a hospital: The effect of complying with the universal precautions policy. Infect Control Hosp Epidemiol 1992; 13: 719-724.

    Google Scholar 

  16. Hardt F, Aldershvile J, Dietrichson O, et al. Hepatitis B virus infections among Danish surgeons. J Infect Dis 1979; 140: 972-974.

    Google Scholar 

  17. Skinhoj P, Vinterberg H, Aldershvile J, Kryger P. Hepatitis A, B, and non-A, non-B in Danish hospital nursing staff. J Clin Pathol 1984; 37: 763-766.

    Google Scholar 

  18. Skinhoj P. Epidemiology of hepatitis B antigen and antibody in hospital patients in Copenhagen. Scand J Infect Dis 1975; 7: 85-89.

    Google Scholar 

  19. Struve J, Aronsson B, Frenning B, Forsgren M, Weiland O. Prevalence of antibodies against hepatitis C virus infection among health care workers in Stockholm. Scand J Gastroenterol 1994; 29: 360-362.

    Google Scholar 

  20. Thorburn D, Dundas D, McCruden EA, et al. A study of hepatitis C prevalence in healthcare workers in the West of Scotland. Gut 2001; 48: 116-120.

    Google Scholar 

  21. Nelsing S, Nielsen TL, Bronnum-Hansen H, Nielsen JO. Incidence and risk factors of occupational blood exposure: A nation-wide survey among Danish doctors. Eur J Epidemiol 1997; 13: 1-8.

    Google Scholar 

  22. Nelsing S, Nielsen TL, Nielsen JO. Underreporting and follow up of exposure to blood among Danish physicians. Ugeskr Laeger 1997; 159: 6211-6215.

    Google Scholar 

  23. Nash GF, Goon P. Current attitudes to surgical needlestick injuries. Ann R Coll Surg Engl 2000; 82(Suppl 7): 236-237.

    Google Scholar 

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Authors and Affiliations

  1. Department of Clinical Immunology, Odense University Hospital, Denmark

    Niels Fisker, Jørgen Georgsen & Peer B. Christensen

  2. Department of Internal Medicine, Odense University Hospital, Odense C, Denmark

    Lone H. Mygind

  3. Department of Clinical Chemistry, Aalborg Hospital, Hobrovej 18–22, Aalborg, Denmark

    Henrik B. Krarup

  4. Department of Clinical Microbiology, Odense University Hospital, Odense C, Denmark

    Dorthe Licht

Authors
  1. Niels Fisker
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  2. Lone H. Mygind
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  3. Henrik B. Krarup
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  4. Dorthe Licht
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  5. Jørgen Georgsen
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  6. Peer B. Christensen
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Fisker, N., Mygind, L.H., Krarup, H.B. et al. Blood borne viral infections among Danish Health Care Workers – frequent blood exposure but low prevalence of infection. Eur J Epidemiol 19, 61–67 (2004). https://doi.org/10.1023/B:EJEP.0000013397.51614.d4

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  • DOI: https://doi.org/10.1023/B:EJEP.0000013397.51614.d4

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