Public HealthUSE OF PERTUSSIS VACCINE IN AN EPIDEMIC INVOLVING HOSPITAL STAFF
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Cited by (146)
Development of carbohydrate based next-generation anti-pertussis vaccines
2022, Bioorganic and Medicinal ChemistryCitation Excerpt :Since wP vaccines were developed and standardized, the number of Bp related deaths decreased22 by more than 75% compared with the pre-vaccine era.23 However, the wP vaccine was associated with some safety issues, as it can occasionally have serious adverse effects such as local reactions, fever, and seizures.24 With the increasing public scrutiny on vaccine safety, a safer acellular vaccine (aP) composed of pertussis toxin and filamentous hemagglutinin was introduced in Japan in 1981.
Vaccines for Healthcare Personnel
2017, Plotkin's VaccinesSeroprevalence of pertussis amongst healthcare professionals in Spain
2016, VaccineCitation Excerpt :Within the general population, healthcare professionals form an important subset as they may act as vectors facilitating the transmission of pertussis amongst their patients, especially in immunosuppressed individuals. At the hospital level, the transmission of pertussis may occur between visitors and patients and between healthcare personnel and patients, or vice versa [11–14]. Given the risk of transmission to the most vulnerable populations in the hospitals (newborns, premature babies, etc.) [11–13], several countries have recommended vaccination to healthcare workers.