Lead exposure and the cognitive development of urban preschool children: The cincinnati lead study cohort at age 4 years

doi:10.1016/0892-0362(91)90012-L

Neurotoxicology and Teratology

Volume 13, Issue 2, March–April 1991, Pages 203-211

https://doi.org/10.1016/0892-0362(91)90012-L Get rights and content

Abstract

The purpose of this analysis was to determine if significant associations could be observed between prenatal/postnatal blood lead (PbB) levels and the cognitive development of 258 urban, inner-city children at 4 years of age. These children have been followed since birth with frequent assessments of general health, PbB, and neuropsychological status. The Kaufman Assessment Battery for Children (K-ABC) was administered at approximately 4 years of age. Higher neonatal PbB levels were associated with poorer performance on all K-ABC subscales. However, this inverse association was limited to children from the poorest families. Maternal PbB levels were unrelated to 4-year cognitive status. Few statistically significant associations between postnatal PbB levels and K-ABC scales could be found. However, the results did suggest a weak inverse relationship between postnatal PbB levels and performance on a K-ABC subscale which assesses visual-spatial and visual-motor integration skills. In these results we note both contradiction and accord with previously published prospective studies.

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ArticleLead exposure and the cognitive development of urban preschool children: The cincinnati lead study cohort at age 4 years

Abstract

J. Pediatr.

Neurotoxicol. Teratol.

Environ. Res.

Neurotoxicol. Teratol.

Chronological trend in blood lead levels between 1976 and 1980

N. Engl. J. Med.

Home observation for measurement of the environment

Preventing lead poisoning in young children: A statement by the Centers for Disease Control, January 1985

Simultaneous and successive processes and K-ABC

J. Special Education

Contribution of social and developmental factors to lead exposure during the first year of life

Pediatrics

Low-level fetal lead exposure effect on neurobehavioral development in early infancy

Pediatrics

The neurobehavioral effects of early lead exposure

Monogr. Am. Assoc. Ment. Defic.

The effects of foetal and postnatal lead exposure on neurobehavioral development during the first year of life

Article
Lead exposure and the cognitive development of urban preschool children: The cincinnati lead study cohort at age 4 years