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The role of chlorine oxide radical (ClO<sup>•</sup>) in the degradation of polychoro-1,3-butadienes in UV/chlorine treatment: kinetics and mechanisms
2020, Water ResearchCitation Excerpt :The concentrations of HCBD range μg L−1 in water and μg kg−1 in soil (or organism), respectively (Chen et al., 2015; Zhang et al., 2014). HCBD can induce nephrotoxicity, reproduction toxicity and exert potential carcinogenicity (Booker and Pavlostathis, 2000; Brüschweiler et al., 2010; Schwetz et al., 1977). HCBD has been considered as a persistent organic pollutant and listed in Annex C of the Stockholm Convention (Wang et al., 2018).
Recently listed Stockholm convention POPs: Analytical methodology, occurrence in food and dietary exposure
2019, Science of the Total EnvironmentCitation Excerpt :The main adverse effect reported (Yang et al., 1989) was kidney damage in dosed rodents (dose ranges: 0.2–2.0 mg/kg bw/day) and damage to the liver and nervous system (Kociba et al., 1977) at a higher dose of 20 mg/kg bw/day. Retardation of foetal growth in rats (Schwetz et al., 1977) dosed at 20 mg/kg bw/day has also been reported. Information on other species is scarce, but available evidence suggests that HCBD is toxic to birds and very toxic to aquatic organisms (UNEP, 2012).
Development of resistance against hexachlorobutadiene in the proximal tubules of young male rat
2003, Comparative Biochemistry and Physiology - C Toxicology and PharmacologyAppendix C: Chlorinated alkenes
1994, Regulatory Toxicology and PharmacologyInhalation teratology study on hexachloro-1,3-butadiene in rats
1989, Toxicology LettersPotential halogenated industrial carcinogenic and mutagenic chemicals I. Halogenated unsaturated hydrocarbons
1979, Science of the Total Environment, The