Review
The veterans administration-army cooperative study of pulmonary function: I. Clinical spirometry in normal men☆

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Abstract

  • 1.

    1. A standardized procedure for clinical spirometry is described which was formulated by a Veterans Administration-Army Cooperative Group for pulmonary function testing.

  • 2.

    2. Spirometric studies of 468 normal men were contributed by fifteen participating pulmonary function laboratories. The nineteen parameters measured were tabulated and analyzed with the aid of an electronic computer.

  • 3.

    3. Mean values and standard deviations were calculated for each measurement.

  • 4.

    4. A product-moment correlation matrix was constructed which shows the relationship of each measurement to the other eighteen measurements.

  • 5.

    5. Of the several physical measurements, age and height showed the highest correlations with VC, FEV0.5, FEV1.0 and MVVF. Regression equations for these ventilatory measurements were constructed upon age and height.

  • 6.

    6. A nomogram is presented which can be used to obtain simultaneously the predicted normal values for VC, FEV0.5, FEV1.0 and MVVF.

  • 7.

    7. Cross validation of the prediction formulas with two sets of independent data demonstrates that the Veterans Administration-Army prediction formulas have retained their reliability and have the highest cross-validation coefficients of any formulas now available.

  • 8.

    8. The weakness implicit in the use of BSA in constructing prediction formulas for spirometric measurements is discussed.

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    • Cited by (0)

    ☆

    The investigators and pulmonary function laboratories of the fifteen hospitals contributing to this study are listed under Acknowledgments.

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