Epidemiological assessment of the role of physical activity and fitness in development of cardiovascular disease

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      Heart rate data may be an early indicator of HCT complications. Elevated heart rate is related to subclinical loss of cardiac reserve [39] and poor physical fitness [27]. In normotensive patients, elevated HR measured by continuous HR tracking is predictive of cardiovascular and noncardiovascular death [26], and elevated heart rate has been identified as a predictor of in-hospital mortality risk for HCT patients [40,41].

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