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Occupational Exposures and Risk of Adenocarcinoma of the Lung in Uruguay

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Abstract

Objectives:

To investigate occupational risks of lung adenocarcinoma in Uruguay and to confirm a previously reported increased risk among butchers.

Methods:

We conducted a case–control study among men in four major hospitals in Montevideo, based on interviews to 338 cases of lung adenocarcinoma and 1014 hospital-based controls. We calculated odds ratios (ORs) of lung adenocarcinoma for employment in 22 jobs, after adjustment for tobacco smoking and other potential confounders.

Results:

The OR was increased for employment as farmer, tractor driver, painter and medical worker, but no trend was suggested for duration of employment. Long-term employment as mason, glass worker or textile worker resulted in an increased OR. The OR for employment as butcher was 1.2 (95% confidence interval 0.7–2.1). The OR increased with increasing duration of self-reported exposure to formaldehyde.

Conclusions:

Occupational exposures seem to play a limited role in causing lung adenocarcinoma among men in Uruguay. Employment as butcher was not confirmed as an important risk factor.

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Correspondence to Paolo Boffetta.

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Stefani, E.D., Boffetta, P., Brennan, P. et al. Occupational Exposures and Risk of Adenocarcinoma of the Lung in Uruguay. Cancer Causes Control 16, 851–856 (2005). https://doi.org/10.1007/s10552-005-2819-4

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  • DOI: https://doi.org/10.1007/s10552-005-2819-4

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