Summary
The effects of lead exposure on psychological test performance and subjective feelings of well-being were investigated in 40 exposed workers whose PbB levels had never exceeded 60 μg/100 ml and in 20 controls matched for sex, age and educational level. The exposed workers were divided into two groups of 20, with recent PbB levels in the range 45–60 μg/100 ml or below 35 μg/100 ml. The group of workers with the higher PbB levels showed significantly poorer performance and reported more physical symptoms than the other two groups. These differences were unrelated to socio-demographic and personality characteristics. A principal component analysis suggested that the poorer performance was mainly due to an impairment of general functioning and only to some extent to a deterioration in specific functions, such as verbal reasoning and abstraction. Higher lead concentrations were correlated with poorer performance and a higher number of physical complaints. These results indicate that in exposed workers the threshold for impaired performance lies below the blood-lead concentration of 60 μg/100 ml, which is the current threshold limit value (TLV).
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References
Araki S, Homma T (1976) Relationship between lead absorption and peripheral nerve conduction velocities in lead workers. Scand J Work Environ Health 2:225–231
Cardiani A, Farina G (1972) Influenza del consumo di bevande alcooliche sulle alterazioni della biosintesi dell'eme indotte dal piombo. Med Lav 63:22–28
Cramer K (1966) Predisposing factors for lead poisoning. Acta Med Scand [Suppl] 445:56–59
D'Andrea F, Apostoli G, Colli M, Minoia C, Piemonte G, Pozzoli L (1979) Controllo interlaboratoriale della determinazione della piombemia. In: Gaffuri E, D'Andrea F (eds) Rischi, patologia e prevenzione nell'industria degli accumulatori. Zendrini, Verona, pp 187–204
Eysenck HJ (1959) Manual of the Maudsley peronality inventory. University of London Press, London
Goldberg D (1972) The detection of psychiatric illness by questionnaire. Oxford University Press, London
Goyer RA, Chisolm JJ (1978) Lead. In: Lee DHK (ed) Metallic contaminants and human health. Academic Press, New York, pp 57–95
Grandjean Ph, Arnvig E, Beckmann J (1978) Psychological dysfunctions in lead-exposed workers. Relation to biological parameters of exposure. Scand J Work Environ Health 4:295–303
Hänninen H (1979) Psychological test methods: sensitivity to long term chemical exposure at work. Neurobehav Toxicol [Suppl] 1:157–161
Hänninen J, Lindström K (1979) Behavioral test battery for toxicopsychological studies used at the Institute of Occupational Health in Helsinki, 2nd revised edn. Institute of Occupational Health, Helsinki
Hänninen H, Hernberg S, Mantere P, Vesanto R, Jalkanen M (1978) Psychological performance of subjects with low exposure to lead. J Oral Med 20:683–689
Hänninen H, Mantere P, Hernberg S, Seppäläinen AM, Kock B (1979) Subjective symptoms in low-level exposure to lead. Neurotoxicology 1:333–347
Hessel D (1968) A simple and rapid quantitative determination of lead in blood. At Absorp New 7:55–56
Lison L (1961) Statistica Applicata alla Biologia Sperimentale. Casa Editrice Ambrosiana, Milano
Magid E, Hilden M (1975) Elevated levels of blood lead in alcoholic liver disease. Int Arch Occup Environ Health 35:61–65
Morrison DF (1976) Multvariate statistical methods, 2nd edn. McGraw-Hill, Kogakusha, Tokyo, pp 266–301
Repko JD, Morgan BB, Nicholson JA (1975) Behavioural effects of occupational exposure to lead. USDHEW (NIOSH) Publication no. 75–164, Washington, DC
Repko JD, Corum CR, Jones PD, Garcia LS (1978) The effects of inorganic lead on behavioral and neurologic function. Final report. USDHEW (NIOSH) Publication no. 78–128, Washington,
Seppäläinen AM, Hänninen H, Hernberg S (1976) Effect of lead on the central and peripheral nervous system. Second International Workshop on Permissible Levels for Occupational Exposure to Inorganic Lead. Amsterdam, September 20–24
Seppäläinen AM, Tola S, Hernberg S, Kock B (1975) Subclinical neuropathy at “safe” levels of lead exposure. Arch Environ Health 30:180–183
Tansella M, Fiorio R, D'Andrea F (1979) Indagine su frequenza di disturbi emotivi e consumo di psicofarmaci in lavoratori esposti al piombo in una industria di accumulatori. In: Gaffuri E, D'Andrea F (eds) Rischi, patologia e prevenzione nell'industria degli accumulatori. Zendrini, Verona, pp 179–186
Tarnopolsky A, Barker SM, Wiggins RD, McLean EK (1978) The effect of aircraft noise on the mental health of a community sample: a pilot study. Psychol Med 8:219–233
Valciukas JA, Lilis R (1980) Psychometric techniques in environmental research. Environ Res 21:275–297
Valciukas JA, Lilis R, Eisinger J, Blumber WE, Fischbein A, Sclikoff IJ (1978) Behavioral indicators of lead neurotoxicity: results of a clinical field surgery. Int Arch Occup Environ Health 41:217–236
Valciukas JA, Lilis R, Petrocci M (1981) An integrative index of biological effects of lead. Am J Ind Med 2:261–272
World Health Organization (1977) Environmental health criteria. Lead. WHO, Geneva
Zimmermann-Tansella Ch (1979) The effects of benzodiazepines on psychological performance in normal subjects and anxious patients. PhD Thesis, University of London, London
Zimmermann-Tansella Ch, Campara P, D'Andrea F, Savonitto C, Tansella M (1983) Psychological and physical complaints of subjects with low exposure to lead. Human Toxicol 2:615–623
Zimmermann-Tansella Ch, Tansella M, Lader M (1976) The effects of chlordesmethyldiazepam on behavioural performance and subjective judgement in normal subjects. J Clin Pharmacol 16:481–488
Zimmermann-Tansella Ch, Tansella M, Lader M (1979) A comparison of the clinical and psychological effects of diazepam and amylobarbitone in anxious inpatients. Br J Clin Pharmacol 7:605–611
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This study was supported by the Consiglio Nazionale delle Ricerche (CNR, Roma), Gruppo Nazionale Scienze del Comportamento (Grant no. 81.00083.04 and no. 82.02117.04)
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Campara, P., D'Andrea, F., Micciolo, R. et al. Psychological performance of workers with blood-lead concentration below the current threshold limit value. Int. Arch Occup Environ Heath 53, 233–246 (1984). https://doi.org/10.1007/BF00398816
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DOI: https://doi.org/10.1007/BF00398816