Abstract
The prevalence of positive skin-prick test reactions to ammonium persulphate and potassium persulphate (1% and 5% solutions) was tested in a cross-sectional study on 52 employees of a company producing persulphates after a case of “persulphate asthma” was observed. A random test of 13 persons without occupational exposure to persulphates served as controls; among them all the skin-prick test reactions were negative. Eight company employees showed a positive skin-prick test reaction to at least one of the persulphate solutions tested. Employees showed lower lung function results with a positive prick test reaction than did employees with a negative result. The positive skin-prick reactions correspond well to the anamnestic data and indicate a possible relationship to obstructive ventilation disorders. The results therefore suggest an IgE-induced, allergic pathomechanism of “persulphate asthma” triggered by persulphates.
Similar content being viewed by others
References
Bates DV, Gothsch AR, Brooks S, Landrigan PJ, Hankinson JL, Merchant JA (1992) Prevention of occupational lung disease. Chest 102 [Suppl]:257–276
Baur X (1992) Berufsbedingte Atemwegskrankheiten allergischer, chemisch-irritativer und toxischer Genese. Atemwegs-Lungenkrankheiten 18:460–462
Baur X, Fruhmann G (1979) Berufsbedingte Asthma bronchiale allergischer und chemisch irritativer Genese. Prax Pneumol 33:317–322
Blainey AD, Ollier S, Cundell D, Smith RE, Davie RJ (1986) Occupational asthma in a hairdressing salon. Thorax 41:42–50
Cloutier Y, Lagier F, Cartier A, Malo JL (1992) Validation of an exposure system to particles for the diagnosis of occupational asthma. Chest 102:402–407
Commission of the European Community (CEC) (1971) Leitfaden für die praktische Durchführung der Untersuchung der ventilatorischen Funktion durch die Spirographie. Schriften Arbeitshyg Arbeitsmed 11
Drexler H, Schiele R, Lehnert G (1992) Berufsbedingte obstruktive Atemwegserkrankungen im Friseurhandwerk. Verh Dtsch Ges Arbeitsmed 32:193–196
Drexler H, Schaller K-H, Weber A, Letzel S, Lehnert G (1993) Skin prick tests with solutions of acid anhydrides in acetone. Int Arch Allergy Immunol 100:251–255
Fisher AA, Dooms-Goossens A (1976) Persulfate hair bleach reactions. Cutaneous and respiratory manifestions. Arch Dermatol 112:1407–1409
Gamboa PM, de la Cuesta CG, Garcia BE, Castillo JG, Oehling A (1989) Late asthmatic reaction in a hairdresser, due to the inhalation of ammonium persulphate salts. Allergol Immunopathol 17:109–111
Kleinhans D, Ranneberg KM (1989) Sofortreaktionen durch Ammoniumpersulfat in Blondierpulvern. Allergologie 12:353–354
Koelsch F (1962) Handbuch der Berufskrankheiten, 3rd edn. Fischer, Jena
Lahti A, Maibach HI (1993) Immediate contact contact reactions. In: Manning S et al (eds) Allergy, principles and practice. Mosby-Year Book, Chicago
Mapp CE, Saetta M, Maestrelli P, Ciaccia A, Fabbri LM (1994) Low molecular weight pollutants and asthma: pathogenetic mechanisms and genetic factors. Eur Respir J 7:1559–1563
Meindl K, Meyer R (1969) Asthma und Urtikaria im Friseurberuf durch Persulfat-haltige Blondiermittel. Zentralbl Arbeitsmed 3:75–79
Mensing T, Marek W, Pothast J, Baur X (1994) Zum Pathomechanismus oxidierender Substanzen des Friseurhandwerks im Atemtrakt. Atemwegs-Lungenkrankheit 20:450–451
Pankow W, Hein H, Bittner K, von Wichert P (1989) Persulfat-Asthma im Friseurberuf. Pneumologie 43:173–175
Parra FM, Igea JM, Ouirce S, Ferrando MC, Martin JA, Losada E (1992) Occupational asthma in a hairdresser caused by persulphate salts. Allergy 47:656–660
Pepys J, Hutchcroft BJ, Breslin ABX (1976) Asthma due to agents — perulfate salts and henna in hairdressers. Clin Allergy 6:399–404
Ring J (1988) Angewandte Allergologie. MMW Medizin, Munich
Salkie ML (1991) The Phadiatop test allows adequate screening for atopy with a marked reduction in cost. J Clin Lab Anal 5:226–227
Schwab W (1978) Gewerbeallergien der oberen Luftwege. Allergologie 1:167–171
Schwaiblmair M, Baur X, Fruhmann G (1990) Asthma bronchiale durch Blondiermittel im Friseurberuf. Dtsch Med Wochenschr 115:695–697
Shamssain MH (1995) Respiratory symptoms and pulmonary function in flour processing workers in the baking industry. Am J Ind Med 27:359–365
Van der Walle HB, Brunsveld M (1994) Dermatitis in hairdressers. I. The experience of the past 4 years. Contact Dermatitis 30:217–221
Welinder H, Jönsson AG, Nielsen JE, Ottosson HE, Gustavsson CA (1994) Exposure-response relationships in the formation of specific antibodies to hexahydrophthalic anhydride in exposed workers. Scand J Work Environ Health 20:459–465
Wrbitzky R, Drexler H (1995) Persulfat-Asthma bei einer Chemie-laborantin. Arbeitsmed Sozialmed Umweltmed 30:366–369
Zelger J, Huber W (1992) Meche-Brei-Allergien. In: Baumgartner E (ed) Verhandlungen der Österreichischen Gesellschaft für Arbeitsmedizin. Maudrich, Vienna, pp 50–62
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Wrbitzky, R., Drexler, H. & Letzel, S. Early reaction type allergies and diseases of the respiratory passages in employees from persulphate production. Int. Arch Occup Environ Heath 67, 413–417 (1995). https://doi.org/10.1007/BF00381054
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00381054