Regular ArticleHuman Ingestion of Chromium (VI) in Drinking Water: Pharmacokinetics Following Repeated Exposure
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Lung function assessment and its association with blood chromium in a chromate exposed population
2022, Science of the Total EnvironmentCitation Excerpt :Considering spirometry is noninvasive and invaluable as a screening examination of general respiratory health, the reference value in present article may have significance to some extent; 3) Food pattern was not included as a covariate, and the source of blood Cr was not considered. However, several studies have shown that by observing the toxicokinetics of Cr(III) and Cr(VI) ingested by the human volunteers, soluble Cr(VI) compounds are absorbed to a greater extent than soluble Cr(III) compounds (Finley et al., 1997; Finley et al., 1996; Kerger et al., 1997; Kerger et al., 1996a; Kerger et al., 1996b; Paustenbach et al., 1996). Actually, we also roughly collected their dietary preferences and place of residence in questionnaire survey, which suggested that their dietary patterns were similar.
Chromium
2021, Handbook on the Toxicology of Metals: Fifth EditionPhysiology-based toxicokinetic modelling in the frame of the European Human Biomonitoring Initiative
2019, Environmental ResearchPhysiologically-based pharmacokinetic and toxicokinetic models for estimating human exposure to five toxic elements through oral ingestion
2018, Environmental Toxicology and PharmacologyCitation Excerpt :It has been observed that human absorption of Cr(VI) in the GI tract can vary between individuals and also in the same individual at different times, with suggestions that physiological fluids in the GI tract such as gastric juice and diet constituents (for instance orange juice) can lead to poor intestinal absorption of Cr(VI), because of their capacities to reduce Cr(VI) to Cr(III) (De Flora et al., 1997; Kerger et al., 1996; Sasso and Schlosser, 2015). Intra-individual variability in Cr(VI) absorption due to differences in this reduction capacity has been noted in studies involving human subjects (Finley et al., 1997; Paustenbach et al., 1996; O’Flaherty et al., 2001). Absorption values of 0.25 day−1 for Cr(III) and 2.5 day−1 for Cr(VI) were specified by O’Flaherty et al. (2001).