Regular ArticleEstimation of a Chromium Inhalation Reference Concentration Using the Benchmark Dose Method: A Case Study
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Dysregulation of MiR-199a/IL8 pathway in chronic Cr (VI)-induced tumor growth and angiogenesis
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2021, Regulatory Toxicology and PharmacologyCitation Excerpt :Noncancer data amenable to modeling were not presented in Glaser et al. (1986); therefore, selected noncancer endpoints were modeled from subchronic rat inhalation studies (Glaser et al., 1985, 1990). Selection of endpoints was informed by Malsch et al. (1994), who modeled various endpoints well before the release of the US EPA's BMD software. Similar to the cancer modeling, air concentrations were extrapolated to HEC using information presented in Supplemental Table 6 and were used to model the various effects shown in Supplemental Table 7.
Different roles of ROS and Nrf2 in Cr(VI)-induced inflammatory responses in normal and Cr(VI)-transformed cells
2016, Toxicology and Applied PharmacologyCitation Excerpt :Hexavalent chromium Cr(VI) is classified as a human carcinogen. Exposure to Cr(VI) occurs in multiple occupational environments due to its commercial usage in welding, chrome pigmenting, leather tanning, and ferrochrome industry (Fishbein, 1981; Malsch et al., 1994). Cr(VI) is also a component of industrial waste and atmospheric pollution.
Levels of metals in soils of Alcalá de Henares, Spain: Human health risks
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