HR (95% CI) all-cause mortality | HR (95% CI) for cancer incidence | |||
Fully adjusted* |
Fully adjusted*
sarin only exposed† | Fully adjusted* |
Fully adjusted*
sarin only exposed‡ | |
Sarin exposure | ||||
(yes/no) | 1.08 (1.01 to 1.16) | 1.08 (1.00 to 1.18) | 1.01 (0.93 to 1.10) | 1.05 (0.94 to 1.17) |
Number of sarin tests | ||||
1 | 1.06 (0.99 to 1.14) | 1.07 (0.98 to 1.17) | 1.00 (0.92 to 1.10) | 1.04 (0.93 to 1.16) |
2 or more | 1.25 (1.04 to 1.49) | 1.26 (1.00 to 1.59) | 1.09 (0.85 to 1.38) | 1.04 (0.76 to 1.43) |
Dose | ||||
Unknown | 1.10 (0.99 to 1.22) | 1.13 (1.01 to 1.27) | 1.03 (0.91 to 1.17) | 1.06 (0.91 to 1.24) |
Low (air<15 mg.min/m3) | 1.04 (0.95 to 1.13) | 1.03 (0.92 to 1.15) | 0.99 (0.89 to 1.11) | 1.01 (0.88 to 1.16) |
High (air>15 mg.min/m3) | 1.15 (1.02 to 1.30) | 1.15 (0.94 to 1.41) | 1.01 (0.87 to 1.18) | 1.07 (0.83 to 1.38) |
State§ | ||||
Vapour | 1.07 (1.00 to 1.15) | 1.08 (0.98 to 1.18) | 1.01 (0.92 to 1.10) | 1.05 (0.93 to 1.18) |
Liquid | 1.10 (0.96 to 1.27) | 1.11 (0.96 to 1.29) | 1.02 (0.85 to 1.23) | 1.01 (0.83 to 1.23) |
Physical protection | ||||
No | 1.11 (1.03 to 1.20) | 1.11 (1.01 to 1.23) | 1.02 (0.93 to 1.13) | 1.12 (0.99 to 1.26) |
Yes | 1.00 (0.90 to 1.12) | 1.03 (0.91 to1.17) | 0.96 (0.84 to 1.11) | 0.89 (0.75 to 1.06) |
Chemical protection | ||||
No | 1.06 (0.99 to 1.15) | 1.08 (0.99 to 1.19) | 1.01 (0.92 to 1.11) | 1.04 (0.92 to 1.17) |
Yes | 1.13 (1.01 to 1.26) | 1.10 (0.93 to 1.29) | 1.01 (0.88 to 1.17) | 1.05 (0.85 to 1.29) |
All-cause mortality models based on 2975 sarin-exposed veterans and 2919 ‘Non-Porton Down veterans’ (reference) over an average 52.2-year follow-up. Cancer incidence models based on 2899 sarin-exposed veterans and 2853 ‘Non-Porton Down veterans’ (reference), over an average 49.8-year follow-up
*Adjusted for age, calendar period, branch of service, previous duration of service and place of birth.
†Estimates based on 1430 veterans exposed to sarin only (allowing for co-exposure to rubber mixes and mustard sensitivity tests).
‡Estimates based on 1385 veterans exposed to sarin only (allowing for co-exposure to rubber mixes and mustard sensitivity tests).
§Excludes 47 veterans with missing state data.