HRs for the association between attendance at Porton Down and cause-specific mortality in 2975 Porton Down veterans and 2919 non-Porton Down veterans
| Observed deaths (n) | HR (95% CI) | |||||
| Any sarin exposure | Sarin-only exposure* | |||||
| Cause of death (ICD-10 code) | Porton Down veterans | Non-Porton Down veterans | Adjusted for age and calendar period | Fully adjusted† | Fully adjusted† | Fully adjusted†—excluding physical protection |
| All-cause | 1598 | 1583 | 1.08 (1.01 to 1.16) | 1.08 (1.01 to 1.16) | 1.08 (1.00 to 1.18) | 1.12 (1.01 to 1.23) |
| Infectious and parasitic (A00–B99) | 17 | 10 | 1.88 (0.86 to 4.12) | 1.97 (0.89 to 4.36) | 1.55 (0.60 to 4.05) | 0.91 (0.25 to 3.35) |
| Malignant neoplasms (All) (C00–C97) | 543 | 534 | 1.08 (0.96 to 1.22) | 1.07 (0.95 to 1.21) | 1.14 (0.98 to 1.31) | 1.24 (1.06 to 1.46) |
|
Upper aerodigestive (C00–C14 and C30–C32) | 20 | 17 | 1.21 (0.63 to 2.32) | 1.20 (0.63 to 2.29) | 1.13 (0.49 to 2.58) | 1.59 (0.70 to 3.59) |
| Oesophageal (C15) | 37 | 37 | 1.05 (0.66 to 1.65) | 1.03 (0.65 to 1.62) | 1.05 (0.60 to 1.86) | 1.00 (0.52 to 1.92) |
| Intestine and rectum (C17–C20) | 55 | 45 | 1.29 (0.87 to 1.92) | 1.30 (0.87 to 1.93) | 1.61 (1.03 to 2.52) | 1.77 (1.08 to 2.90) |
| Trachea, bronchus and lung (C33 and C34) | 159 | 157 | 1.07 (0.86 to 1.34) | 1.06 (0.85 to 1.32) | 1.08 (0.82 to 1.41) | 1.32 (0.99 to 1.76) |
| Brain and other central nervous system (C71 and C72) | 16 | 15 | 1.09 (0.54 to 2.21) | 1.08 (0.53 to 2.19) | 1.54 (0.65 to 3.62) | 1.69 (0.68 to 4.21) |
| All lymphatic and haematopoietic (C81–C96) | 44 | 44 | 1.05 (0.69 to 1.60) | 1.04 (0.69 to 1.58) | 1.00 (0.61 to 1.65) | 1.04 (0.58 to 1.84) |
| Nervous system (G00–G99) | 49 | 68 | 0.77 (0.53 to 1.12) | 0.78 (0.54 to 1.13) | 0.72 (0.44 to 1.16) | 0.62 (0.34 to 1.13) |
| Circulatory system all (I00–I99) | 540 | 536 | 1.08 (0.96 to 1.22) | 1.08 (0.95 to 1.21) | 1.10 (0.95 to 1.27) | 1.13 (0.96 to 1.33) |
| Ischaemic heart diseases (I20–I25) | 345 | 343 | 1.07 (0.92 to 1.24) | 1.06 (0.91 to 1.23) | 1.03 (0.86 to 1.24) | 1.04 (0.84 to 1.28) |
| Cerebrovascular diseases (I60–I69) | 87 | 108 | 0.89 (0.67 to 1.19) | 0.88 (0.66 to 1.17) | 1.00 (0.71 to 1.39) | 0.97 (0.66 to 1.43) |
| All other circulatory (I00–I19, I26–I59 and I70–I99) | 108 | 85 | 1.38 (1.03 to 1.83) | 1.41 (1.06 to 1.87) | 1.49 (1.08 to 2.08) | 1.76 (1.22 to 2.52) |
| Respiratory system all (J00–J99) | 148 | 158 | 1.05 (0.83 to 1.31) | 1.05 (0.84 to 1.32) | 0.97 (0.73 to 1.28) | 0.84 (0.59 to 1.18) |
| Chronic lower respiratory tract (J40–J47) | 81 | 86 | 1.03 (0.76 to 1.40) | 1.03 (0.76 to 1.40) | 1.04 (0.72 to 1.50) | 0.86 (0.54 to 1.35) |
| All other respiratory (J00–39 and J48–99) | 67 | 72 | 1.07 (0.76 to 1.49) | 1.07 (0.76 to 1.50) | 0.87 (0.57 to 1.35) | 0.80 (0.47 to 1.35) |
| Digestive system (K00–K93) | 72 | 53 | 1.42 (0.99 to 2.02) | 1.42 (1.00 to 2.03) | 1.34 (0.88 to 2.04) | 1.42 (0.89 to 2.28) |
| Genitourinary system (N00–N99) | 21 | 18 | 1.23 (0.65 to 2.31) | 1.25 (0.67 to 2.35) | 0.82 (0.36 to 1.84) | 0.92 (0.36 to 2.33) |
| All external causes (S00–T98 and V01–Y98) | 75 | 69 | 1.10 (0.79 to 1.53) | 1.10 (0.79 to 1.52) | 1.12 (0.74 to 1.70) | 1.14 (0.71 to 1.83) |
| Alcohol attributable (F102, K701, K703, K704 and K709) | 33 | 13 | 2.60 (1.37 to 4.94) | 2.66 (1.40 to 5.07) | 2.12 (0.98 to 4.58) | 2.66 (1.18 to 5.99) |
| Smoking-related (highly causal only; C33, C34 and J40–J44) | 237 | 240 | 1.06 (0.88 to 1.27) | 1.05 (0.87 to 1.25) | 1.07 (0.86 to 1.33) | 1.16 (0.91 to 1.48) |
| No ICD code | 58 | 40 | 1.54 (1.03 to 2.31) | 1.57 (1.04 to 2.35) | 1.38 (0.85 to 2.25) | 1.31 (0.74 to 2.33) |
Reference category: ‘non-Porton Down veterans’
*1430 Porton Down veterans exposed to sarin only (allowing for co-exposure to rubber mixes and mustard sensitivity tests).
†Adjusted for branch of service, previous duration of service, period of joining and place of birth.
ICD-10, International Classification of Diseases, 10th revision.