Associations between lifetime occupational exposure to known sensitisers and current asthma or asthma symptom score
| Current asthma | Asthma symptoms score | |||||||||
| Men (n=47 873) | Women (n=59 426) | P interaction | Men (n=50 438) | Women (n=61 454) | P interaction | |||||
| n | OR (95% CI) | n | OR (95% CI) | n | Mean score ratio (95% CI) | n | Mean score ratio (95% CI) | |||
| Ref | 26 922 | 1 | 37 157 | 1 | 28 504 | 1 | 43 315 | 1 | ||
| HMW sensitisers | 38 174 | 51 180 | 35 019 | 52 958 | ||||||
| Exposed | 6240 | 1.12 (1.02 to 1.22) | 14 023 | 1.05 (0.98 to 1.11) | 0.41 | 6515 | 1.16 (1.10 to 1.23) | 14 471 | 1.05 (1.02 to 1.09) | 0.001 |
| Medium | 3893 | 1.09 (0.98 to 1.22) | 6670 | 1.00 (0.91 to 1.09) | 0.51 | 4063 | 1.17 (1.09 to 1.24) | 6704 | 1.05 (1.01 to 1.10) | 0.01 |
| High | 2347 | 1.16 (1.02 to 1.33) | 7533 | 1.09 (1.00 to 1.18) | 0.94 | 2452 | 1.16 (1.07 to 1.25) | 7767 | 1.06 (1.01 to 1.11) | 0.04 |
| LMW sensitisers | 39 307 | 50 950 | 41 377 | 52 711 | ||||||
| Exposed | 12 385 | 0.96 (0.89 to 1.03) | 13 793 | 1.03 (0.96 to 1.09) | 0.04 | 12 873 | 1.09 (1.05 to 1.14) | 14 224 | 1.04 (1.00 to 1.08) | 0.06 |
| Medium | 9353 | 0.95 (0.88 to 1.03) | 12 333 | 1.03 (0.97 to 1.11) | 0.12 | 9733 | 1.06 (1.02 to 1.12) | 12 714 | 1.03 (1.00 to 1.07) | 0.28 |
| High | 3032 | 0.99 (0.87 to 1.12) | 1460 | 0.96 (0.81 to 1.14) | 0.67 | 3140 | 1.18 (1.10 to 1.27) | 1510 | 1.09 (0.99 to 1.19) | 0.15 |
Logistic regressions and binomial negative regressions adjusted for age, BMI and smoking habits. Results in boldface are statistically significant.
BMI, body mass index; HMW, high molecular weight; LMW, low molecular weight.