Table 1

Malignant mesothelioma (MM) cases in young (<50 years old at diagnosis) and eldest adults (>50 years) by gender, anatomical site, incidence period, diagnostic certainty, morphology and modalities of exposure detection

		MM cases (<50 years old)		MM cases (>50 years old)
		N.	%	N.	%
Gender	Women	443	34.7	8214	27.8
Gender	Men	835	65.3	21 336	72.2
Anatomical site	Pleura	1058	82.8	27 685	93.7
	Peritoneum	194	15.2	1742	5.9
	Pericardium	13	1.0	48	0.2
	Tunica vaginalis of testis	13	1.0	75	0.3
Incidence period	1993–1998	214	16.7	2545	8.6
	1999–2003	338	26.4	5428	18.4
	2004–2008	298	23.3	6854	23.2
	2009–2013	263	20.6	7889	26.7
	2014–2018	165	12.9	6834	23.1
Diagnostic certainty	Defined MM	1167	91.3	23 821	80.6
Diagnostic certainty	Probable or possible MM	111	8.7	5729	19.4
Morphology*	Epithelioid	805	69.0	16 338	68.6
	Biphasic	182	15.6	2947	12.4
	Sarcomatous	59	5.1	2112	8.9
	MM NOS	121	10.4	2424	10.2
Exposure detection	Interview to the patient	697	54.5	12 933	43.8
	Interview to a relative	299	23.4	10 148	34.3
	Other	2	0.2	150	0.5
	No interview	280	21.9	6319	21.4
Overall		1278		29 550

Italian national mesothelioma registry (ReNaM), 1993–2018.
*Only defined MM.
NOS, not otherwise specified.