ORs and 95% CIs for TGCT associated with occupations, according to employment duration (<2 vs ≥2 years), TESTIS study
| Occupation description (ISCO-68)* | Ca/Co (never) | Ca/Co<2 Years | OR1 (95% CI)† | Ca/Co≥2 Years | OR2 (95% CI)† | P trend |
| Professional, technical and related workers (0/1) | 254/355 | 27/42 | 0.81 (0.48 to 1.39) | 139/253 | 0.83 (0.62 to 1.10) | 0.38 |
| Architects, engineers and related technicians (0–2/0–3) | 368/567 | 12/22 | 0.72 (0.33 to 1.50) | 40/61 | 1.03 (0.66 to 1.62) | 0.68 |
| Teachers (1–3) | 391/593 | 7/20 | 0.62 (0.25 to 1.50) | 22/37 | 0.94 (0.53 to 1.68) | 0.56 |
| Administrative and managerial workers (2) | 366/544 | 13/26 | 0.82 (0.41 to 1.68) | 41/80 | 0.88 (0.57 to 1.34) | 0.74 |
| Clerical and related workers (3) | 334/523 | 38/42 | 1.37 (0.85 to 2.22) | 48/85 | 0.84 (0.87 to 1.26) | 0.27 |
| Sales workers (4) | 332/538 | 30/37 | 1.28 (0.76 to 2.15) | 58/75 | 1.28 (0.87 to 1.88) | 0.34 |
| Salesmen, shop assistants and related workers (4–5) | 365/597 | 25/22 | 1.81 (0.98 to 3.33) | 30/31 | 1.54 (0.90 to 2.66) | 0.06 |
| Salesmen, shop assistants and demonstrators (4–51) | 365/603 | 25/18 | 2.12 (1.12 to 4.02) | 30/29 | 1.65 (0.95 to 2.87) | 0.02 |
| Retail trade salesman (4–51.30) | 391/622 | 16/13 | 1.77 (0.82 to 3.81) | 13/15 | 1.33 (0.61 to 2.92) | 0.27 |
| Other salesmen, shop assistants and demonstrators (4–51.90) | 388/631 | 22/9 | 3.58 (1.59 to 8.06) | 10/10 | 1.55 (0.61 to 3.95) | <0.01 |
| Service workers (5) | 319/510 | 32/37 | 1.31 (0.78 to 2.20) | 69/103 | 1.11 (0.78 to 1.58) | 0.53 |
| Cooks, waiters, bartenders and related workers (5–3) | 377/592 | 18/21 | 1.28 (0.66 to 2.51) | 25/37 | 1.16 (0.67 to 2.00) | 0.68 |
| Waiters, bartenders and related workers (5–32) | 393/621 | 13/9 | 2.58 (1.07 to 6.24) | 14/20 | 1.22 (0.58 to 2.53) | 0.10 |
| Waiter, general (5–32.10) | 399/631 | 13/7 | 3.38 (1.28 to 8.94) | 8/12 | 1.11 (0.43 to 2.86) | 0.05 |
| Protective service workers (5–8) | 385/602 | 7/10 | 1.11 (0.40 to 3.10) | 28/38 | 1.10 (0.65 to 1.87) | 0.92 |
| Protective service workers N.E.C (5–89) | 396/617 | 8/10 | 1.41 (0.52 to 3.79) | 16/23 | 1.04 (0.52 to 2.04) | 0.79 |
| Watchman (5–89.40) | 409/634 | 6/6 | 1.25 (0.37 to 4.22) | 5/10 | 1.00 (0.34 to 2.99) | 0.94 |
| Agricultural, animal husbandry and forestry workers (6) | 375/611 | 13/11 | 1.71 (0.73 to 3.98) | 32/28 | 1.71 (0.99 to 2.95) | 0.08 |
| Agricultural and animal husbandry workers (6–2) | 384/619 | 14/11 | 1.81 (0.78 to 4.19) | 22/20 | 1.65 (0.86 to 3.15) | 0.13 |
| Production and related workers, transport equipment operators and labourers (7/8/9) | 216/385 | 43/66 | 1.06 (0.68 to 1.66) | 161/199 | 1.45 (1.09 to 1.94) | 0.03 |
| Production supervisors and general foremen (7–0) | 399/620 | 6/13 | 0.78 (0.29 to 2.13) | 15/17 | 1.62 (0.78 to 3.36) | 0.38 |
| Machinery fitters, machine assemblers and precision-instrument makers (except electrical) (8–4) | 362/593 | 23/14 | 2.50 (1.24 to 5.06) | 35/43 | 1.43 (0.87 to 2.34) | 0.02 |
| Motor-vehicle mechanics (8–43) | 406/631 | 7/9 | 1.12 (0.39 to 3.17) | 7/10 | 1.19 (0.44 to 3.26) | 0.92 |
| Machinery fitters, machine assemblers and precision-instrument makers (except electrical) N.E.C (8–49) | 388/618 | 15/9 | 2.65 (1.12 to 6.26) | 17/23 | 1.16 (0.59 to 2.30) | 0.08 |
| Electrical fitters and related electrical and electronics workers (8–5) | 378/613 | 15/14 | 1.75 (0.81 to 3.76) | 27/23 | 1.83 (1.01 to 3.32) | 0.06 |
| Electrical wiremen (8–55) | 394/626 | 8/8 | 1.39 (0.50 to 3.88) | 18/16 | 1.77 (0.87 to 3.60) | 0.24 |
| Plumbers, welders, sheet-metal and structural metal preparers and erectors (8–7) | 388/620 | 16/10 | 2.23 (0.96 to 5.20) | 16/20 | 1.36 (0.67 to 2.75) | 0.13 |
| Welders and flame-cutters (8–72) | 408/638 | 7/6 | 1.31 (0.41 to 4.17) | 5/6 | 1.51 (0.44 to 5.21) | 0.73 |
| Bricklayers, carpenters and other construction workers (9–5) | 380/601 | 16/16 | 1.75 (0.84 to 3.67) | 24/33 | 1.05 (0.60 to 1.86) | 0.33 |
| Material handling and related equipment operators, dockers and freight handlers (9–7) | 374/594 | 26/31 | 1.39 (0.79 to 2.45) | 20/25 | 1.15 (0.61 to 2.18) | 0.49 |
| Transport equipment operators (9–8) | 386/599 | 16/29 | 0.81 (0.42 to 1.59) | 18/22 | 1.31 (0.67 to 2.54) | 0.60 |
Boldface indicates a p value <0.05.
*Total number of subjects presented for each code can vary due to the management of codes with missing digits. Subjects with a single job coded as missing data, were excluded from the analyses (N=33).
†Estimates obtained comparing TGCT cases to group A and group B controls combined and adjusted for sibship size, being born from multiple pregnancy, personal history of testicular trauma, family history of TGCT and family history of cryptorchidism. Analysis was restricted to subjects with no missing data for the adjustment variables (N=12). Results presented if a job was held by more than five cases and five controls.
Ca/Co (ever)/(never), cases/controls ever/never employed; ISCO, International Standard Classification of Occupations; N.E.C, not elsewhere classified; TGCT, testicular germ cell tumour.