ORs and 95% CIs for TGCT associated with industries, overall and cording to histological subtypes, TESTIS study
| Industry description (NAF-99 code)* | All TGCT cases | Seminomas‡ | Non-seminomas§ | P-HET¶ | |||
| Ca/Co (%ever) | OR (95% CI)† | Ca/Co (%ever) | OR (95% CI)† | Ca/Co (%ever) | OR (95% CI)† | ||
| Agriculture, hunting and forestry (01, 02) | 7.9/5.2 | 1.43 (0.85 to 2.41) | 7.5/5.3 | 1.32 (0.69 to 2.54) | 9.8/5.3 | 1.64 (0.83 to 3.25) | 0.65 |
| Agriculture, hunting and related service activities (01) | 7.6/4.8 | 1.56 (0.91 to 2.67) | 7.5/4.8 | 1.48 (0.76 to 2.88) | 9.1/4.8 | 1.79 (0.88 to 3.64) | 0.70 |
| Manufacturing (15–37) | 31.3/29.4 | 1.10 (0.83 to 1.46) | 31.3/29.4 | 1.13 (0.79 to 1.61) | 29.3/29.4 | 1.00 (0.67 to 1.50) | 0.66 |
| Publishing, printing and reproduction of recorded media (22) | 1.7/1.1 | 1.67 (0.56 to 4.99) | |||||
| Metalworking (28) | 3.8/4.6 | 0.84 (0.44 to 1.61) | 3.7/4.7 | 0.82 (0.35 to 1.89) | 4.3/4.7 | 0.92 (0.37 to 2.34) | 0.85 |
| Electricity, gas and water supply (40, 41) | 3.6/2.9 | 1.12 (0.53 to 2.36) | 2.3/2.9 | 0.80 (0.28 to 2.28) | 3.7/2.9 | 0.88 (0.32 to 2.40) | 0.90 |
| Electricity, gas, steam and hot water supply (40) | 2.9/2.6 | 0.98 (0.44 to 2.19) | 2.3/2.6 | 0.85 (0.29 to 2.46) | 3.0/2.6 | 0.75 (0.25 to 2.25) | 0.88 |
| Construction (45) | 20.5/16.6 | 1.27 (0.91 to 1.77) | 16.8/16.4 | 0.94 (0.61 to 1.47) | 22.6/16.4 | 1.41 (0.89 to 2.22) | 0.22 |
| Site preparation (45.1) | 1.2/1.2 | 0.76 (0.23 to 2.50) | |||||
| Construction of building and civil engineering works (45.2) | 6.2/4.7 | 1.38 (0.78 to 2.43) | 3.3/4.7 | 0.61 (0.26 to 1.47) | 9.1/4.7 | 1.80 (0.88 to 3.66) | 0.06 |
| Installation work (45.3) | 11.2/6.4 | 1.99 (1.25 to 3.15) | 9.4/6.4 | 1.52 (0.84 to 2.75) | 9.8/6.4 | 1.59 (0.83 to 3.03) | 0.92 |
| Electrical installation work (45.3A) | 6.9/4.04 | 1.98 (1.12 to 3.50) | 6.6/4.1 | 1.66 (0.82 to 3.38) | 6.1/4.1 | 1.96 (0.89 to 4.34) | 0.76 |
| Installation of heating and air conditioning equipment (45.3F) | 3.3/1.2 | 2.95 (1.18 to 7.39) | |||||
| Finishing work (45.4) | 5.0/5.3 | 0.87 (0.48 to 1.56) | 4.7/5.1 | 0.82 (0.38 to 1.78) | 6.1/5.1 | 1.15 (0.53 to 2.51) | 0.54 |
| Trade, repair of motor vehicles and household goods (50–52) | 30.1/23.7 | 1.42 (1.06 to 1.90) | 31.8/23.8 | 1.34 (0.94 to 1.92) | 28.0/23.8 | 1.41 (0.93 to 2.14) | 0.86 |
| Motor trade and repair (50) | 5.7/4.2 | 1.40 (0.78 to 2.52) | 7.5/4.2 | 1.59 (0.81 to 3.12) | 4.3/4.2 | 1.16 (0.47 to 2.86) | 0.57 |
| Wholesale trade and commercial intermediaries (51) | 10.5/8.2 | 1.35 (0.87 to 2.10) | 10.7/8.2 | 1.25 (0.73 to 2.16) | 11.0/8.2 | 1.44 (0.79 to 2.65) | 0.73 |
| Retail trade and repair of household goods (52) | 17.7/13.7 | 1.38 (0.97 to 1.96) | 17.3/13.0 | 1.18 (0.76 to 1.82) | 17.1/13.0 | 1.46 (0.90 to 2.39) | 0.52 |
| Retail sale in non-specialised shops (52.1) | 7.4/4.3 | 1.91 (1.11 to 3.28) | 5.6/4.3 | 1.29 (0.63 to 2.66) | 9.8/4.3 | 3.00 (1.51 to 5.98) | 0.10 |
| Supermarkets (52.1D) | 7.2/3.5 | 2.28 (1.28 to 4.06) | 5.6/3.6 | 1.64 (0.78 to 3.46) | 9.1/3.6 | 3.20 (1.55 to 6.60) | 0.21 |
| Food retail in specialised shops (52.2) | 2.4/1.1 | 2.89 (1.03 to 8.14) | |||||
| Hotels and restaurants (55) | 12.2/10.6 | 1.23 (0.82 to 1.84) | 11.2/10.5 | 1.07 (0.63 to 1.79) | 14.0/10.5 | 1.34 (0.79 to 2.29) | 0.56 |
| Transport and communications (60–64) | 10.7/14.5 | 0.74 (0.50 to 1.09) | 14.0/14.6 | 0.94 (0.59 to 1.50) | 7.3/14.6 | 0.49 (0.26 to 0.94) | 0.10 |
| Financial activities (65–67) | 4.8/5.4 | 1.05 (0.58 to 1.88) | 4.7/5.4 | 0.95 (0.45 to 2.03) | 6.1/5.4 | 1.72 (0.80 to 3.69) | 0.29 |
| Real estate, rental and business services (70–74) | 24.1/30.2 | 0.77 (0.57 to 1.03) | 29.0/30.3 | 0.91 (0.63 to 1.31) | 17.1/30.3 | 0.51 (0.32 to 0.81) | 0.05 |
| Other business activities (74) | 14.8/16.6 | 0.91 (0.64 to 1.30) | 17.8/16.7 | 1.06 (0.69 to 1.63) | 8.5/16.7 | 0.50 (0.27 to 0.92) | 0.04 |
| Public administration (75) | 16.9/16.5 | 0.98 (0.69 to 1.38) | 15.9/16.6 | 0.83 (0.52 to 1.30) | 18.9/16.6 | 1.15 (0.71 to 1.86) | 0.33 |
| Education (80) | 22.7/23.9 | 0.97 (0.72 to 1.31) | 21.0/24.0 | 0.78 (0.52 to 1.15) | 23.2/24.0 | 0.99 (0.65 to 1.51) | 0.41 |
| Secondary education (80.2) | 15.8/12.3 | 1.33 (0.92 to 1.92) | 15.0/12.4 | 1.03 (0.64 to 1.66) | 15.2/12.4 | 1.27 (0.76 to 2.13) | 0.55 |
| General secondary education (80.2A) | 3.1/3.3 | 0.88 (0.41 to 1.88) | 2.8/3.3 | 0.50 (0.18 to 1.41) | 3.0/3.3 | 1.33 (0.46 to 3.86) | 0.20 |
| Technical or professional secondary education (80.2C) | 12.9/8.9 | 1.55 (1.03 to 2.34) | 12.1/8.9 | 1.31 (0.78 to 2.21) | 12.8/8.9 | 1.35 (0.77 to 2.39) | 0.94 |
| Health and social work (85) | 7.4/12.9 | 0.57 (0.37 to 0.89) | 8.4/13.0 | 0.64 (0.36 to 1.11) | 7.9/13.0 | 0.61 (0.32 to 1.16) | 0.92 |
| Human health activities (85.1) | 5.5/9.7 | 0.56 (0.33 to 0.93) | 4.7/9.8 | 0.45 (0.22 to 0.93) | 7.9/9.8 | 0.79 (0.41 to 1.52) | 0.26 |
| Hospital activities (85.1A) | 4.5/7.9 | 0.56 (0.32 to 0.98) | 2.8/7.9 | 0.33 (0.13 to 0.81) | 7.9/7.9 | 1.01 (0.52 to 1.96) | 0.04 |
| Other community, social and personal services (90–93) | 14.1/10.9 | 1.48 (1.00 to 2.19) | 13.6/11.0 | 1.23 (0.75 to 2.01) | 16.5/11.0 | 2.26 (1.32 to 3.87) | 0.10 |
| Recreational, cultural and sporting activities (92) | 10.5/8.6 | 1.40 (0.91 to 2.17) | 9.8/8.7 | 1.09 (0.62 to 1.90) | 12.2/8.7 | 2.07 (1.14 to 3.76) | 0.12 |
Boldface indicates a p value <0.05.
*Total number of subjects presented for each code can vary due to the management of codes with missing digits. Subjects with a single job coded as missing data, were excluded from the analyses (N=33).
†Estimates obtained comparing TGCT cases to group A and group B controls combined and adjusted for sibship size, being born from multiple pregnancy, personal history of testicular trauma, family history of TGCT and family history of cryptorchidism. Analysis was restricted to subjects with no missing data for the adjustment variables (N=12). Results presented if a job was held by more than five cases and five controls (grey line if less).
‡219 cases of seminoma TGCT were present in the TESTIS study.
§191 cases of non-seminoma TGCT were present in the TESTIS study.
¶ P-value for heterogeneity derived from the Likelihood Ratio Test, comparing seminoma versus non-seminoma tumours.
Ca/Co (%ever), percentage of cases/controls ever employed; ISCO, International Standard Classification of Occupations; NAF-99, Nomenclature d’Activités Française-1999; N.E.C, not elsewhere classified; P-HET, P-value for heterogeneity; TGCT, testicular germ cell tumour.