Association between time-varying occupational noise exposure and stroke incidence DCH cohort only
| N cases | Model 1* HR (95% CI) | Model 2† HR (95% CI) | Model 3‡ HR (95% CI) | |
| Occupational noise (all participants)§ | ||||
| <70 dB(A) | 2460 | Reference | Reference | Reference |
| 70–74 dB(A) | 1015 | 1.04 (0.97 to 1.12) | 1.01 (0.94 to 1.09) | 0.99 (0.92 to 1.07) |
| 75–79 dB(A) | 483 | 1.09 (0.99 to 1.21) | 1.04 (0.94 to 1.15) | 1.01 (0.91 to 1.12) |
| 80–84 dB(A) | 206 | 1.10 (0.95 to 1.27) | 1.03 (0.90 to 1.20) | 1.00 (0.86 to 1.15) |
| ≥85 dB(A) | 272 | 1.21 (1.06 to 1.37) | 1.12 (0.99 to 1.28) | 1.08 (0.95 to 1.23) |
| Occupational noise (up to 5 years back)¶ | ||||
| <70 dB(A) | 1059 | Reference | Reference | Reference |
| 70–74 dB(A) | 452 | 1.16 (1.04 to 1.30) | 1.12 (1.00 to 1.25) | 1.09 (0.97 to 1.22) |
| 75–79 dB(A) | 207 | 1.11 (0.95 to 1.28) | 1.04 (0.89 to 1.21) | 1.00 (0.86 to 1.17) |
| 80–84 dB(A) | 78 | 1.01 (0.80 to 1.27) | 0.93 (0.74 to 1.18) | 0.89 (0.70 to 1.12) |
| ≥85 dB(A) | 122 | 1.33 (1.10 to 1.61) | 1.22 (1.01 to 1.49) | 1.16 (0.95 to 1.41) |
| Occupational noise (up to 1-year back)** | ||||
| <70 dB(A) | 645 | Reference | Reference | Reference |
| 70–74 dB(A) | 282 | 1.22 (1.06 to 1.40) | 1.17 (1.01 to 1.35) | 1.14 (0.99 to 1.32) |
| 75–79 dB(A) | 126 | 1.09 (0.90 to 1.32) | 1.03 (0.84 to 1.25) | 0.99 (0.81 to 1.20) |
| 80–84 dB(A) | 50 | 1.02 (0.77 to 1.36) | 0.95 (0.71 to 1.27) | 0.90 (0.67 to 1.21) |
| ≥85 dB(A) | 76 | 1.47 (1.15 to 1.87) | 1.34 (1.05 to 1.73) | 1.27 (0.99 to 1.63) |
*Adjusted for age, sex and calendar year at baseline (5-year period).
†Model 1 plus adjustment for educational level (low, medium, high), marital status (married/cohabiting, single), area-income (quartiles).
‡Model 2 plus adjustment for smoking status (never, former, current), and physical activity (low, medium, high).
§Time-varying occupational noise exposure during follow-up, and handling persons outside the workforce by taking their latest occupational noise exposure.
¶Time-varying occupation noise exposure, censoring all participants 5 years after last occupation noise exposure.
**Time-varying occupation noise exposure, censoring all participants 1 year after last occupation noise exposure.
DCH, Diet, Cancer and Health.