Table 2

Changes in estimated glomerular filtration rate based on creatinine, cystatin C and both creatinine and cystatin C over a harvest season in male sugarcane cutters from Nicaragua (n=360) and El Salvador (n=98)

eGFRcreGFRcrcyseGFRcyseGFRmean
Nicaragua
eGFR before harvest (95% CI)101 (99 to 103)88 (85 to 89)78 (76 to 80)90 (88 to 92)
eGFR at end of harvest (95% CI)98 (95 to 100)85 (83 to 87)76 (74 to 78)87 (85 to 89)
Difference eGFR (95% CI)−3 (−5 to −2)−3 (−4 to −1)−2 (−3 to −1)−3 (−4 to −1)
% change (95% CI)−3 (−5 to −2)−3 (−5 to −2)−3 (−4 to −1)−3 (−4 to −2)
P value**<0.001<0.0010.003<0.001
El Salvador
eGFR before harvest (95% CI)105 (99 to 111)98 (92 to 105)93 (86 to 100)99 (93 to 105)
eGFR at end of harvest (95% CI)101 (94 to 108)95 (88 to 101)90 (82 to 97)95 (88 to 102)
Difference eGFR (95% CI)−4 (−6 to −2)−4 (−6 to −2)−3 (−6 to −1)−4 (−6 to −2)
% change (95% CI)−4 (−6 to −2)−4 (−6 to −2)−4 (−7 to −1)−4 (−6 to −2)
P value**<0.0010.0010.019<0.001
  • *Significance evaluated with paired t-test.

  • eGFR, estimated glomerular filtration rate; eGFRcr, estimated glomerular filtration rate based on creatinine; eGFRcrcys, estimated glomerular filtration rate based on both creatinine and cystatin C; eGFRcys, estimated glomerular filtration rate based on cystatin C; eGFRmean, mean between creatinine and cystatin C based estimated glomerular filtration rate.