Table 2

Association of history and duration of high occupational physical activity with cause-specific mortality, by sex

NeverEver
0 year<1 year1–2 years3–5 years6–9 years≥10 yearsTotal (ever)
Men, n89 582784713 72219 68112 13543 90597 290
 Deaths from cancer, cases768862811911772113744969224
 Age adjusted1 (Reference)0.95 (0.87 to 1.04)1.03 (0.96 to 1.10)1.10 (1.04 to 1.16)1.16 (1.09 to 1.24)1.27 (1.22 to 1.31)1.16 (1.12 to 1.20)
 Multivariable-adjusted model 11 (Reference)0.98 (0.90 to 1.07)1.04 (0.98 to 1.11)1.08 (1.02 to 1.14)1.10 (1.04 to 1.18)1.11 (1.06 to 1.16)1.08 (1.05 to 1.12)
 Multivariable-adjusted model 21 (Reference)0.97 (0.89 to 1.06)1.01 (0.94 to 1.07)1.04 (0.98 to 1.10)1.05 (0.98 to 1.12)1.06 (1.02 to 1.11)1.04 (1.01 to 1.07)
 Multivariable-adjusted model 3*1 (Reference)0.97 (0.89 to 1.05)1.01 (0.95 to 1.07)1.03 (0.98 to 1.09)1.04 (0.98 to 1.11)1.06 (1.01 to 1.10)1.04 (1.00 to 1.07)
 Deaths from CVD, cases73665699861568103844508611
 Age-adjusted1 (Reference)0.91 (0.83 to 0.99)0.90 (0.84 to 0.97)1.03 (0.97 to 1.09)1.12 (1.05 to 1.20)1.33 (1.28 to 1.38)1.15 (1.11 to 1.18)
 Multivariable-adjusted model 11 (Reference)0.94 (0.86 to 1.02)0.92 (0.86 to 0.99)1.01 (0.95 to 1.07)1.07 (0.99 to 1.15)1.13 (1.08 to 1.15)1.05 (1.01 to 1.08)
 Multivariable-adjusted model 21 (Reference)0.95 (0.85 to 1.02)0.90 (0.84 to 0.96)0.99 (0.94 to 1.04)1.04 (0.97 to 1.11)1.11 (1.06 to 1.16)1.03 (0.99 to 1.06)
 Multivariable-adjusted model 3†1 (Reference)0.94 (0.87 to 1.03)0.89 (0.83 to 0.95)0.98 (0.93 to 1.04)1.03 (0.96 to 1.10)1.10 (1.06 to 1.15)1.02 (0.98 to 1.05)
 Deaths from non-cancer/CVD, cases7208562997155797741548247
 Age adjusted1 (Reference)0.91 (0.84 to 0.99)0.93 (0.87 to 0.99)1.05 (0.99 to 1.10)1.08 (1.01 to 1.15)1.27 (1.22 to 1.32)1.12 (1.09 to 1.16)
 Multivariable-adjusted model 11 (Reference)0.95 (0.87 to 1.03)0.95 (0.89 to 1.01)1.02 (0.97 to 1.08)1.02 (0.95 to 1.09)1.07 (1.03 to 1.12)1.03 (0.99 to 1.05)
 Multivariable-adjusted model 21 (Reference)0.95 (0.87 to 1.04)0.93 (0.87 to 0.99)1.02 (0.96 to 1.07)1.01 (0.95 to 1.08)1.07 (1.02 to 1.12)1.02 (0.99 to 1.05)
 Multivariable-adjusted model 31 (Reference)0.95 (0.87 to 1.04)0.93 (0.87 to 0.99)0.99 (0.94 to 1.05)0.98 (0.92 to 1.05)1.04 (0.99 to 1.08)0.99 (0.97 to 1.03)
Women, n113 552140721313729312211 31321 702
 Deaths from cancer, cases77711051442612588391607
 Age adjusted1 (Reference)1.21 (0.99 to 1.48)1.11 (0.93 to 1.32)1.18 (1.04 to 1.35)1.37 (1.21 to 1.57)1.14 (1.06 to 1.23)1.18 (1.12 to 1.25)
 Multivariable-adjusted model 11 (Reference)1.18 (0.96 to 1.45)1.08 (0.90 to 1.28)1.15 (1.01 to 1.31)1.33 (1.17 to 1.52)1.08 (1.00 to 1.17)1.13 (1.07 to 1.20)
 Multivariable-adjusted model 21 (Reference)1.12 (0.91 to 1.38)1.02 (0.86 to 1.22)1.06 (0.93 to 1.21)1.22 (1.07 to 1.40)1.03 (0.95 to 1.11)1.07 (1.01 to 1.13)
 Multivariable-adjusted model 3*1 (Reference)1.10 (0.90 to 1.33)1.02 (0.87 to 1.21)1.03 (0.91 to 1.16)1.20 (1.06 to 1.36)1.03 (0.96 to 1.11)1.07 (1.00 to 1.15)
 Deaths from CVD, cases5783741012071726581212
 Age adjusted1 (Reference)1.20 (0.95 to 1.50)1.11 (0.91 to 1.35)1.32 (1.15 to 1.51)1.30 (1.11 to 1.50)1.26 (1.16 to 1.37)1.26 (1.18 to 1.34)
 Multivariable-adjusted model 11 (Reference)1.11 (0.89 to 1.40)1.05 (0.86 to 1.27)1.24 (1.08 to 1.42)1.19 (1.02 to 1.39)1.12 (1.04 to 1.22)1.14 (1.08 to 1.22)
 Multivariable-adjusted model 21 (Reference)1.07 (0.85 to 1.34)1.03 (0.84 to 1.25)1.17 (1.02 to 1.35)1.14 (0.98 to 1.33)1.08 (0.99 to 1.17)1.10 (1.03 to 1.17)
 Multivariable-adjusted model 3†1 (Reference)1.03 (0.82 to 1.29)1.02 (0.83 to 1.24)1.15 (1.00 to 1.33)1.11 (0.95 to 1.29)1.06 (0.97 to 1.15)1.04 (0.97 to 1.10)
 Deaths from non-cancer/CVD, cases7310891462561928531536
 Age-adjusted1 (Reference)1.12 (0.91 to 1.39)1.24 (1.05 to 1.46)1.26 (1.11 to 1.43)1.12 (0.97 to 1.29)1.28 (1.19 to 1.37)1.24 (1.17 to 1.31)
 Multivariable-adjusted model 11 (Reference)1.06 (0.86 to 1.31)1.18 (0.99 to 1.39)1.19 (1.05 to 1.35)1.04 (0.90 to 1.19)1.15 (1.07 to 1.24)1.14 (1.07 to 1.21)
 Multivariable-adjusted model 21 (Reference)1.02 (0.82 to 1.25)1.16 (0.98 to 1.37)1.13 (0.99 to 1.28)0.99 (0.84 to 1.15)1.12 (1.04 to 1.20)1.09 (1.03 to 1.16)
 Multivariable-adjusted model 31 (Reference)0.93 (0.75 to 1.14)1.14 (0.97 to 1.34)1.08 (0.95 to 1.22)0.94 (0.82 to 1.09)1.05 (0.98 to 1.13)1.04 (0.98 to 1.10)
  • SValues are HRs (95% CI). Multivariable-adjusted model 1 was adjusted for socioeconomic factors (age, deprivation index, educational level, race and marital status). Multivariable-adjusted model 2 was adjusted as multivariable-adjusted model 1 plus lifestyle behaviours (energy intake, Healthy Eating Index, smoking status, alcohol intake, leisure time moderate to vigorous physical activity and body mass index categories). Multivariable-adjusted model 3 was adjusted as multivariable-adjusted model 2 plus cardiometabolic risk factors (diabetes, hypertension, hypercholesterolaemia) and chronic health conditions (coronary heart disease, stroke, cancer excluding colorectal cancer, breast cancer and prostate cancer, osteoporosis and pulmonary emphysema.

  • *The cancer variable was not included in this model, since they may be potential precursors (ie, mediators) of cancer mortality.

  • †The diabetes, hypertension, hypercholesterolaemia, coronary heart disease, stroke variables, potential were not included in this model, since they may be potential precursors (ie, mediators) of cardiovascular mortality.

  • CVD, cardiovascular disease.