<50 years | ≥50 years | |||||||
Cases | Controls | OR* | 95% CI | Cases | Controls | OR* | 95% CI | |
Overall | 3319 | 16 125 | 1.02 | 0.98 to 1.07 | 4506 | 22 808 | 0.97 | 0.94 to 1.01 |
Duration of exposure (years) | ||||||||
1–9 | 2674 | 13 071 | 1.02 | 0.97 to 1.07 | 3435 | 16 789 | 1.01 | 0.97 to 1.05 |
10–20 | 484 | 2218 | 1.08 | 0.97 to 1.19 | 629 | 3385 | 0.92 | 0.84 to 1.00 |
>20 | 161 | 836 | 0.94 | 0.80 to 1.12 | 442 | 2634 | 0.83 | 0.75 to 0.92 |
Trend test (p value) | 0.25 | 0.00 | ||||||
Cumulative exposure† | ||||||||
>0%–25% | 780 | 4016 | 0.96 | 0.89 to 1.04 | 1169 | 5674 | 1.01 | 0.95 to 1.08 |
>25%–50% | 848 | 4046 | 1.05 | 0.97 to 1.13 | 1178 | 5722 | 1.01 | 0.95 to 1.08 |
>50%–75% | 842 | 4031 | 1.04 | 0.96 to 1.12 | 1129 | 5707 | 0.97 | 0.91 to 1.04 |
>75% | 849 | 4032 | 1.04 | 0.97 to 1.13 | 1030 | 5705 | 0.89 | 0.83 to 0.95 |
Trend test (p value) | 0.08 | 0.01 | ||||||
Timing of first exposure‡ | ||||||||
Prior to first live birth | 2042 | 9748 | 1.05 | 1.00 to 1.11 | 2257 | 11 124 | 0.99 | 0.94 to 1.04 |
After first live birth | 847 | 4456 | 1.01 | 0.94 to 1.10 | 1780 | 9327 | 0.96 | 0.91 to 1.01 |
Exposure in last held job§ | ||||||||
No | 2440 | 11 922 | 1.01 | 0.97 to 1.06 | 3531 | 17 898 | 0.97 | 0.93 to 1.01 |
Yes | 879 | 4203 | 1.04 | 0.97 to 1.13 | 975 | 4910 | 0.98 | 0.91 to 1.05 |
*Adjusted for parity, age at first live birth and work-related physical activity.
†Exposure level*years summed over employment history and categorised according to percentiles among the controls.
‡Among parous women.
§Among women with lifetime occupational UVR exposure.
UVR, ultraviolet B radiation.