Association between occupational exposures and inflammatory biomarkers
Airborne occupational exposures | Cross-sectional analyses | Longitudinal analyses | |||
(Ln) CRP | (Ln) Eosinophils | (Ln) Neutrophils | Eosinophils (105/L) | Neutrophils (106/L) | |
B* (95% CI) | B* (95% CI) | B* (95% CI) | B* (95% CI) | B* (95% CI) | |
No exposure | Reference | Reference | Reference | Reference | Reference |
Allergens | −0.05 (−0.08 to −0.02) | −0.01 (−0.02 to 0.01) | −0.01 (−0.02 to −0.01) | −12 (−40 to 16) | 18 (−8 to 44) |
Reactive chemicals | −0.05 (−0.08 to −0.02) | 0 (−0.01 to 0.01) | −0.01 (−0.02 to −0.01) | −5 (−34 to 23) | −1 (−27 to 25) |
Pesticides | −0.05 (−0.12 to 0.01) | −0.01 (−0.03 to 0.02) | −0.02 (−0.04 to −0.01) | −24 (−81 to 35) | 51 (−2 to 104) |
Micro-organisms | −0.09 (−0.16 to −0.02) | −0.03 (−0.05 to 00) | −0.02 (−0.03 to −0.01) | −35 (−96 to 26) | 30 (−27 to 86) |
Linear regression models were adjusted for baseline age, sex, BMI, pack-years, smoking, education, monthly income, asthma and medication. The longitudinal analyses were additionally adjusted for time between baseline and follow-up.
Bold: P<0.05.
*B-coefficients of the linear regression analyses.
BMI, body mass index; CRP, C reactive protein.