ERRs of radiation and myeloid neoplasms and leukaemia excluding chronic lymphocytic leukaemia mortality overall and by selected risk factors, US radiologic technologists, 1983–2012
| Characteristics | AML/MDS | AML | Leukaemia excluding CLL | |||
| Number of cases | ERR per 100 mGy (95% CI)* | Number of deaths | ERR per 100 mGy (95% CI)* | Number of deaths | ERR per 100 mGy (95% CI)* | |
| Overall | ||||||
| 116 | 0.015 (<−0.023 to 0.25) | 85 | −0.0002 (<−0.02 to 0.24) | 155 | 0.05 (<−0.09 to 0.24) | |
| Sex | ||||||
| Women | 48 | −0.01 (<−0.02 to 0.45) | 34 | −0.025 (<−0.03 to 0.16) | 62 | 0.003 (<−0.02 to 0.17) |
| Men | 68 | 0.05 (<−0.02 to 0.61) | 41 | 0.02 (<0 to 0.87) | 93 | 0.10 (<−0.02 to 0.40) |
| Year of birth | ||||||
| Before 1930 | 34 | 0.06 (<−0.02 to 0.85) | 20 | 0.02 (<−0.02 to 0.53) | 38 | 0.06 (<−0.02 to 0.28) |
| 1930–1939 | 35 | 0.25 (<0 to 1.4) | 26 | 0.15 (<0.02 to 1.1) | 46 | 0.31 (<−0.02 to 0.31) |
| 1940–1949 | 28 | 0.08 (<−0.02 to 0.91) | 23 | 0.03 (<−0.02 to 0.91) | 43 | 0.21 (<−0.02 to 0.90) |
| 1950 and later | 19 | −0.2 (<−0.2 to 1.4) | 16 | −0.2 (<−0.2 to 1.4) | 28 | −0.2 (<−0.2 to 1.4) |
| Smoking | ||||||
| Never | 42 | 0.06 (<0 to 0.45) | 31 | 0.10 (<−0.02 to 0.74) | 59 | 0.04 (<0.02 to 0.25) |
| Ever | 73 | −0.025 (<−0.2 to 0.37) | 53 | −0.025 (<−0.03 to 0.21) | 95 | 0.07 (<−0.02 to 0.35) |
| Work history | ||||||
| Ever worked with FGI procedures†‡ | 25 | 0.12 (<0 to 0.49) | 21 | 0.20 (−0.02 to 0.80) | 26 | −0.02 (<−0.023 to 0.27) |
| Ever worked with NM procedures†‡ | 27 | 0.06 (<−0.02 to 0.40) | 22 | 0.08 (<−0.02 to 0.48) | 34 | 0.09 (<−0.02 to 0.41) |
*Adjusted for: sex, attained age (log-transformed, continuous), sex, year of birth (continuous), pack-years smoked (continuous).
†No evidence of effect modification by sex, year of birth, ever versus never smoking or ever versus never worked with fluoroscopically guided or with nuclear medicine procedures.
‡As reported in the second cohort survey (1994–1998).
AML, acute myeloid leukaemia; CLL, chronic lymphocytic leukaemia; ERR, excess relative risk; FGI, fluoroscopically-guided interventional; MDS, myelodysplastic syndromes; NM, nuclear medicine.