Characteristics | All CD | CD except CeVD others | Hypertension | IHD | CeVD | Others |
RR (95% CIs) | RR (95% CIs) | RR (95% CIs) | RR (95% CIs) | RR (95% CIs) | RR (95% CIs) | |
Sex | ||||||
Female | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
Male | 0.91 (0.82 to 1.00) | 1.67 (1.43 to 1.95) | 2.43 (1.95 to 3.02) | 2.15 (1.35 to 3.42) | 1.11 (0.68 to 1.81) | 0.44 (0.38 to 0.51) |
Attained age | ||||||
<30 | 1.0 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
30–39 | 0.95 (0.82 to 1.10) | 1.28 (1.02 to 1.60) | 1.50 (1.11 to 2.03) | 1.62 (0.81 to 3.24) | 0.65 (0.30 to 1.38) | 0.80 (0.64 to 1.00) |
40–49 | 1.18 (0.94 to 1.47) | 1.53 (1.14 to 2.07) | 1.97 (1.34 to 2.91) | 1.26 (0.53 to 3.01) | 1.30 (0.47 to 3.63) | 0.74 (0.50 to 1.10) |
≥50 | 1.17 (0.84 to 1.62) | 1.28 (0.84 to 1.95) | 1.56 (0.93 to 2.63) | 1.11 (0.36 to 3.48) | 0.90 (0.20 to 3.94) | 0.83 (0.46 to 1.51) |
Year of birth | ||||||
<1960 | 2.89 (2.05 to 4.07) | 4.18 (2.71 to 6.45) | 5.50 (3.26 to 9.30) | 6.20 (1.88 to 20.49) | 2.40 (0.51 to 11.33) | 4.03 (2.12 to 7.65) |
1960–1969 | 1.93 (1.53 to 2.44) | 2.97 (2.20 to 4.01) | 3.74 (2.58 to 5.43) | 4.62 (1.99 to 10.75) | 1.94 (0.67 to 5.62) | 1.77 (1.16 to 2.70) |
1970–1979 | 1.29 (1.11 to 1.49) | 1.91 (1.56 to 2.35) | 2.28 (1.75 to 2.96) | 2.66 (1.46 to 4.85) | 1.13 (0.55 to 2.29) | 1.10 (0.87 to 1.40) |
≥1980 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
Year of starting work† | ||||||
<1995 | 1.07 (0.90 to 1.29) | 1.27 (1.01 to 1.60) | 1.50 (1.13 to 2.00) | 0.93 (0.52 to 1.66) | 2.07 (0.86 to 4.98) | 0.82 (0.57 to 1.16) |
1995–1999 | 1.00 (0.85 to 1.16) | 1.28 (1.04 to 1.56) | 1.44 (1.12 to 1.85) | 1.27 (0.75 to 2.15) | 1.45 (0.70 to 3.00) | 0.71 (0.53 to 0.94) |
2000–2004 | 1.00 (0.87 to 1.14) | 1.21 (1.00 to 1.45) | 1.23 (0.97 to 1.57) | 1.11 (0.66 to 1.89) | 0.54 (0.23 to 1.25) | 0.90 (0.73 to 1.11) |
≥2005 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
Total years worked‡ | ||||||
<1 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
1–4 | 0.84 (0.65 to 1.07) | 1.06 (0.70 to 1.61) | 1.15 (0.65 to 2.02) | 0.65 (0.22 to 1.97) | 0.27 (0.09 to 0.75) | 0.74 (0.53 to 1.04) |
5–9 | 0.77 (0.60 to 0.98) | 1.07 (0.71 to 1.61) | 1.15 (0.66 to 2.01) | 0.91 (0.32 to 2.59) | 0.30 (0.11 to 0.80) | 0.63 (0.44 to 0.89) |
10–19 | 0.85 (0.66 to 1.09) | 1.25 (0.84 to 1.88) | 1.51 (0.87 to 2.61) | 0.81 (0.29 to 2.28) | 0.51 (0.20 to 1.33) | 0.61 (0.41 to 0.90) |
≥20 | 0.86 (0.64 to 1.15) | 1.22 (0.79 to 1.89) | 1.52 (0.85 to 2.73) | 0.76 (0.26 to 2.28) | 0.66 (0.21 to 2.04) | 0.55 (0.34 to 0.91) |
Smoking | ||||||
Never | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
Former | 1.00 (0.86 to 1.15) | 0.95 (0.80 to 1.12) | 0.98 (0.81 to 1.20) | 0.85 (0.54 to 1.34) | 0.69 (0.36 to 1.35) | 1.16 (0.88 to 1.53) |
Current | 1.00 (0.90 to 1.11) | 1.07 (0.94 to 1.21) | 1.09 (0.94 to 1.26) | 1.04 (0.75 to 1.45) | 0.86 (0.54 to 1.36) | 0.87 (0.70 to 1.09) |
Alcohol intake (days per week) | ||||||
0–1 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
2 | 1.09 (0.99 to 1.21) | 1.13 (1.00 to 1.28) | 1.24 (1.07 to 1.43) | 1.04 (0.75 to 1.45) | 1.04 (0.66 to 1.62) | 1.03 (0.86 to 1.23) |
≥3 | 1.33 (1.13 to 1.55) | 1.43 (1.18 to 1.74) | 1.56 (1.25 to 1.96) | 1.31 (0.76 to 2.24) | 0.78 (0.31 to 1.95) | 1.31 (0.97 to 1.77) |
Family history of heart diseases | ||||||
No | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
Yes | 1.36 (1.20 to 1.53) | 1.49 (1.29 to 1.72) | 1.34 (1.12 to 1.61) | 2.24 (1.58 to 3.17) | 2.07 (1.28 to 3.35) | 1.09 (0.86 to 1.39) |
Family history of hypertension | ||||||
No | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
Yes | 1.60 (1.47 to 1.74) | 2.10 (1.89 to 2.34) | 2.65 (2.32 to 3.02) | 1.55 (1.16 to 2.07) | 1.45 (0.98 to 2.13) | 1.09 (0.93 to 1.26) |
Family history of stroke | ||||||
No | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
Yes | 1.39 (1.25 to 1.56) | 1.52 (1.33 to 1.73) | 1.61 (1.37 to 1.89) | 1.52 (1.06 to 2.19) | 1.60 (0.98 to 2.61) | 1.29 (1.04 to 1.61) |
BMI, kg/m2 | ||||||
<18.5 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
18.5–24.9 | 1.04 (0.84 to 1.28) | 1.19 (0.83 to 1.70) | 1.76 (0.99 to 3.15) | 2.47 (0.60 to 10.15) | 2.08 (0.50 to 8.65) | 1.02 (0.78 to 1.33) |
25.0–29.9 | 1.61 (1.28 to 2.02) | 2.13 (1.47 to 3.07) | 3.73 (2.07 to 6.72) | 3.69 (0.88 to 15.50) | 3.32 (0.76 to 14.50) | 1.14 (0.82 to 1.59) |
≥30.0 | 2.39 (1.72 to 3.33) | 3.63 (2.31 to 5.71) | 6.47 (3.35 to 12.52) | 7.17 (1.42 to 36.21) | 1.86 (0.17 to 20.97) | 1.27 (0.63 to 2.58) |
Blood pressure, mm Hg | ||||||
SBP<120 and DBP<80 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
120≤SBP<140 or 80≤DBP<90 | 1.18 (1.07 to 1.29) | 1.46 (1.28 to 1.67) | 1.89 (1.58 to 2.25) | 1.07 (0.77 to 1.48) | 1.09 (0.70 to 1.67) | 0.92 (0.79 to 1.07) |
SBP≥140 or DBP≥90 | 2.31 (1.99 to 2.68) | 3.39 (2.85 to 4.05) | 5.16 (4.16 to 6.40) | 1.92 (1.15 to 3.22) | 1.80 (0.87 to 3.73) | 0.90 (0.60 to 1.37) |
Total cholesterol, mg/dL | ||||||
<200 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
200–239 | 1.20 (1.08 to 1.32) | 1.30 (1.15 to 1.47) | 1.40 (1.21 to 1.61) | 0.98 (0.68 to 1.41) | 1.73 (1.14 to 2.64) | 0.98 (0.81 to 1.19) |
≥240 | 1.50 (1.27 to 1.76) | 1.82 (1.51 to 2.20) | 1.85 (1.47 to 2.32) | 3.03 (2.01 to 4.57) | 1.55 (0.70 to 3.40) | 0.93 (0.62 to 1.39) |
LDL cholesterol, mg/dL | ||||||
<100 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
100–129 | 0.99 (0.90 to 1.09) | 1.04 (0.92 to 1.18) | 1.13 (0.97 to 1.31) | 0.83 (0.59 to 1.16) | 0.93 (0.60 to 1.46) | 0.93 (0.79 to 1.09) |
130–159 | 1.10 (0.97 to 1.24) | 1.14 (0.98 to 1.33) | 1.25 (1.04 to 1.50) | 0.86 (0.56 to 1.32) | 0.93 (0.52 to 1.68) | 1.10 (0.88 to 1.38) |
≥160 | 1.26 (1.05 to 1.51) | 1.42 (1.14 to 1.76) | 1.54 (1.19 to 2.00) | 1.47 (0.85 to 2.53) | 1.87 (0.93 to 3.78) | 0.96 (0.63 to 1.46) |
HDL cholesterol, mg/dL | ||||||
<40 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
40–59 | 0.87 (0.76 to 0.99) | 0.85 (0.73 to 0.99) | 0.83 (0.69 to 1.00) | 0.81 (0.53 to 1.22) | 0.74 (0.42 to 1.31) | 0.97 (0.73 to 1.28) |
≥60 | 0.80 (0.70 to 0.93) | 0.67 (0.56 to 0.80) | 0.67 (0.54 to 0.82) | 0.64 (0.40 to 1.03) | 0.69 (0.37 to 1.29) | 1.09 (0.81 to 1.46) |
Blood glucose, mg/dL | ||||||
<110 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
110–125 | 0.88 (0.73 to 1.07) | 0.88 (0.70 to 1.10) | 0.92 (0.71 to 1.19) | 0.39 (0.17 to 0.88) | 0.93 (0.43 to 2.03) | 0.78 (0.53 to 1.15) |
≥126 | 1.44 (1.15 to 1.81) | 1.54 (1.19 to 1.99) | 1.61 (1.19 to 2.18) | 1.84 (0.97 to 3.50) | 1.58 (0.58 to 4.30) | 1.32 (0.79 to 2.21) |
*Adjusted for attained age, sex and birth year.
†Based on questionnaire (the year first worked).
‡From the year first worked to the end year of National Dosimetry Registry.
BMI, body mass index; CD, circulatory disease; CeVD, cerebrovascular disease; DBP, diastolic blood pressure; HDL, high-density lipoprotein; IHD, ischaemic heart disease; LDL, low-density lipoprotein; RR, relative risk; SBP, systolic blood pressure.