Styrene exposure level | n | Rate ratio | n | Rate ratio | ||
Men | Women | |||||
Crude | Adjusted* | Crude | Adjusted* | |||
Systemic sclerosis | 22 | 9 | ||||
≤17 mg/m3-years | 1 | 1 | 1 | 1 | ||
18–67 mg/m3-years | 2.52 (0.68 to 9.30) | 1.90 (0.51 to 7.11) | 1.02 (0.19 to 5.58) | 1.15 (0.20 to 6.52) | ||
≥68 mg/m3-years | 2.68 (0.74 to 9.75) | 1.86 (0.50 to 7.00) | 2.13 (0.48 to 9.53) | 2.50 (0.50 to 12.50) | ||
Per 100 mg/m3-years | 1.05 (0.97 to 1.14) | 1.03 (0.94 to 1.13) | 1.18 (1.01 to 1.38) | 1.19 (1.01 to 1.39) | ||
Reumatoid arthritis | 359 | 168 | ||||
≤17 mg/m3-years | 1 | 1 | 1 | 1 | ||
18–67 mg/m3-years | 1.32 (0.99 to 1.76) | 1.12 (0.83 to 1.49) | 0.93 (0.64 to 1.35) | 0.83 (0.57 to 1.20) | ||
≥68 mg/m3-years | 1.68 (1.28 to 2.21) | 1.28 (0.96 to 1.70) | 1.17 (0.80 to 1.71) | 0.95 (0.63 to 1.41) | ||
Per 100 mg/m3-years | 1.04 (1.02 to 1.07) | 1.02 (1.00 to 1.05) | 1.05 (0.97 to 1.13) | 1.01 (0.93 to 1.10) | ||
Systemic lupus erythematosus | 23 | 15 | ||||
≤17 mg/m3-years | 1 | 1 | 1 | 1 | ||
18–67 mg/m3-years | 0.94 (0.36 to 2.45) | 0.84 (0.32 to 2.24) | 1.28 (0.42 to 3.90) | 1.50 (0.47 to 4.73) | ||
≥68 mg/m3-years | 0.60 (0.21 to 1.74) | 0.55 (0.18 to 1.66) | 0.71 (0.15 to 3.35) | 0.88 (0.18 to 4.35) | ||
Per 100 mg/m3-years | 0.70 (0.42 to 1.15) | 0.68 (0.40 to 1.14) | 0.65 (0.24 to 1.77) | 0.71 (0.27 to 1.84) | ||
Small vessel vasculitis | 61 | 19 | ||||
≤17 mg/m3-years | 1 | 1 | 1 | 1 | ||
18–67 mg/m3-years | 1.01 (0.51 to 2.00) | 0.82 (0.41 to 1.64) | 0.79 (0.28 to 2.20) | 0.71 (0.25 to 2.01) | ||
≥68 mg/m3-years | 1.50 (0.80 to 2.81) | 1.06 (0.55 to 2.04) | 0.22 (0.03 to 1.67) | 0.18 (0.02 to 1.38) | ||
Per 100 mg/m3-years | 1.06 (1.01 to 1.11) | 1.03 (0.99 to 1.09) | 0.39 (0.10 to 1.60) | 0.32 (0.07 to 1.47) | ||
Sjögren’s syndrome | 18 | 24 | ||||
≤17 mg/m3-years | 1 | 1 | 1 | 1 | ||
18–67 mg/m3-years | 0.42 (0.13 to 1.39) | 0.40 (0.12 to 1.35) | 1.10 (0.44 to 2.76) | 1.01 (0.40 to 2.55) | ||
≥68 mg/m3-years | 0.60 (0.21 to 1.74) | 0.57 (0.19 to 1.70) | 0.88 (0.29 to 2.68) | 0.79 (0.25 to 2.52) | ||
Per 100 mg/m3-years | 0.75 (0.46 to 1.23) | 0.74 (0.45 to 1.22) | 0.77 (0.42 to 1.42) | 0.73 (0.38 to 1.41) |
*Adjusted for age, calendar year of follow-up and educational level.