Table 2

Correlation between ultrafine particle concentration and respiratory symptoms, and inflammatory parameters, pulmonary function tests and CT score

ParameterUFP concentrationRespiratory symptoms
rP valuerP value
IS IL-80.3360.0240.2840.069
Serum IL-80.6640.010.5420.021
IS IL-60.2940.0650.3690.021
IS TNF-α0.4090.007NDND
IS NLRP30.2720.09NDND
TLC (%)−0.3740.011NDND
FEV1−0.2990.046NDND
DLCOsb (%)−0.4250.004
CT score0.3780.023
CT score0.369*0.021
  • UFP were evaluated by NanoSight LM20 in the IS specimens.

  • P values <0.05 were considered significant for Spearman’s correlation.

  • *Correlation with serum UFP concentration.

  • DLCOsb, diffusion lung carbon monoxide in a single breath; FEV1, forced expiratory volume in 1 s; IL-6, interleukin 6; IL-8, interleukin 8; IS, induced sputum; ND, Not Done; NLRP3, nucleotide-binding domain leucine-rich repeat containing pyrin 3; TLC, total lung capacity; TNF-α, tumour necrosis factor alpha; UFP, ultrafine particles.