Peritoneal mesothelioma OR and 90% CI for expert-based assessment of asbestos exposure based on the national mesothelioma registry (ReNaM) questionnaire, calculated with conditional logistic regression models (set: age category), adjusted for province of residence, education and residual age within age category, Lombardy, Italy, 2008–2015
| Asbestos exposure | Men | Women | ||||||
| Cases | Controls | OR | 90% CI | Cases* | Controls | OR | 90% CI | |
| N (%) | N (%) | N (%) | N (%) | |||||
| Total 2008–2015 | 86 (100) | 141 (100) | 71 (100) | 64 (100) | ||||
| Never exposed | 22 (25.6) | 90 (63.8) | 1.00 | Reference | 45 (63.4) | 59 (92.2) | 1.00 | Reference |
| Ever exposed | 64 (74.4) | 51 (36.2) | 5.78 | 3.03 to 11.0 | 26 (36.6) | 5 (7.8) | 8.00 | 2.56 to 25.0 |
| Source/probability | ||||||||
| Never exposed | 22 (25.6) | 90 (63.8) | 1.00 | Reference | 45 (63.4) | 59 (92.2) | 1.00 | Reference |
| Extra-occupational | 2 (2.3) | 3 (2.1) | 4.12 | 0.62 to 27.1 | 1 (1.4) | 0 (0.0) | NC | NC |
| Occupational, pp | 14 (16.3) | 25 (17.7) | 2.05 | 0.88 to 4.77 | 5 (7.0) | 3 (4.7) | 2.25 | 0.40 to 12.6 |
| Occupational, definite | 48 (55.8) | 23 (16.3) | 12.3 | 5.62 to 26.7 | 20 (28.2) | 2 (3.1) | 14.3 | 3.16 to 65.0 |
| Occupational, duration† | ||||||||
| Never exposed | 22 (26.2) | 90 (65.2) | 1.00 | Reference | 45 (64.3) | 59 (92.2) | 1.00 | Reference |
| <10 years | 13 (15.5) | 16 (11.6) | 3.15 | 1.30 to 7.64 | 11 (15.7) | 0 (0.0) | NC | NC |
| 10–19 years | 10 (11.9) | 9 (6.5) | 7.08 | 2.37 to 21.2 | 10 (14.3) | 4 (6.2) | 3.48 | 0.83 to 14.5 |
| 20–29 years | 8 (9.5) | 7 (5.1) | 4.25 | 1.38 to 13.1 | 2 (2.9) | 0 (0.0) | NC | NC |
| 30+ years | 31 (36.9) | 16 (11.6) | 9.16 | 4.03 to 20.8 | 2 (2.9) | 1 (1.6) | 3.13 | 0.36 to 27.5 |
| P trend | <0.001 | 0.06 | ||||||
| Occupational, duration† (per 10 years) | 1.61 | 1.32 to 1.95 | 1.70 | 0.94 to 3.07 | ||||
| Occupational, TSFE† | ||||||||
| Never exposed | 22 (26.2) | 90 (65.2) | 1.00 | Reference | 45 (64.3) | 59 (92.2) | 1.00 | Reference |
| <40 years | 9 (10.7) | 10 (7.3) | 3.68 | 1.17 to 11.6 | 2 (2.9) | 0 (0.0) | NC | NC |
| 40–49 years | 23 (27.4) | 14 (10.1) | 7.90 | 3.25 to 19.2 | 6 (8.6) | 1 (1.6) | NC | NC |
| 50–59 years | 17 (20.2) | 19 (13.8) | 3.29 | 1.39 to 7.78 | 10 (14.3) | 1 (1.6) | 16.1 | 2.44 to 106 |
| 60+ years | 13 (15.5) | 5 (3.6) | 13.3 | 3.79 to 46.3 | 7 (10.0) | 3 (4.7) | 3.67 | 0.84 to 16.0 |
| P trend | <0.001 | 0.006 | ||||||
Period 2008–2015 includes cases first diagnosed in 2008–2015 and MISEM controls enrolled in 2014; both series living in any province and aged 20–89 years.
*Two female cases with non-classifiable exposure not included in analysis.
†Cases with extra-occupational exposure not included in analysis.
NC, not calculated; pp, possible/probable; ReNaM, Registro Nazionale Mesoteliomi; TSFE, time since first exposure.